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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 8.48
Human Site: S206 Identified Species: 15.56
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S206 C E R A W N H S V R E A G V P
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S206 C E R A W N H S V R E A G V P
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S206 C E L A W N R S V R E A G V P
Dog Lupus familis XP_851664 1092 121456 P198 L P G L P G L P G L G A G A G
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 R206 G R N F T N L R F L Q Q I K S
Rat Rattus norvegicus Q673L6 1125 126915 G206 G G N F T N L G S A H Q I K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 V225 H N S L L D Y V R K R L V F H
Frog Xenopus laevis NP_001079102 1191 137998 F208 R Y I K R N V F H L R K K Y L
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 A204 G A M R K F P A V Q K T V A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 L324 R L I K V Q A L L K A F L T Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 Q221 K Y L C Y L C Q N P E R S Q I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 H190 H K R T L S V H E N K R K R D
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 L34 K C G H F N G L D E I L T T C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 86.6 13.3 N.A. 6.6 6.6 N.A. N.A. 0 6.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 86.6 13.3 N.A. 13.3 6.6 N.A. N.A. 20 6.6 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 24 0 0 8 8 0 8 8 31 0 16 0 % A
% Cys: 24 8 0 8 0 0 8 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 24 0 0 0 0 0 0 8 8 31 0 0 0 0 % E
% Phe: 0 0 0 16 8 8 0 8 8 0 0 8 0 8 0 % F
% Gly: 24 8 16 0 0 8 8 8 8 0 8 0 31 0 8 % G
% His: 16 0 0 8 0 0 16 8 8 0 8 0 0 0 8 % H
% Ile: 0 0 16 0 0 0 0 0 0 0 8 0 16 0 16 % I
% Lys: 16 8 0 16 8 0 0 0 0 16 16 8 16 16 0 % K
% Leu: 8 8 16 16 16 8 24 16 8 24 0 16 8 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 0 0 54 0 0 8 8 0 0 0 0 8 % N
% Pro: 0 8 0 0 8 0 8 8 0 8 0 0 0 0 24 % P
% Gln: 0 0 0 0 0 8 0 8 0 8 8 16 0 8 8 % Q
% Arg: 16 8 24 8 8 0 8 8 8 24 16 16 0 8 0 % R
% Ser: 0 0 8 0 0 8 0 24 8 0 0 0 8 0 8 % S
% Thr: 0 0 0 8 16 0 0 0 0 0 0 8 8 16 0 % T
% Val: 0 0 0 0 8 0 16 8 31 0 0 0 16 24 0 % V
% Trp: 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 8 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _