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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 12.12
Human Site: S231 Identified Species: 22.22
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S231 R G G S A S R S L P L P K R P
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S231 R G G S A S R S L P L P K R P
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S231 R R G S A N R S L P L P K R P
Dog Lupus familis XP_851664 1092 121456 N218 R P T R Q A Q N S G A R R R R
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 P226 A P K P L A L P S R G T K R H
Rat Rattus norvegicus Q673L6 1125 126915 P226 A P K P Q A L P S R G T K R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 S265 R R S H R I Q S L R S G Y Q P
Frog Xenopus laevis NP_001079102 1191 137998 C263 K L C S K D I C V I P D K K R
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 I223 T R D N E K Y I S V K R R R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 T380 Q G S H T K K T S L P P P S Y
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 N260 C S N L D N Q N S R K R K R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 D214 Q W L S S A V D D C P K D D S
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 P53 N S R K I A L P C L P G D L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 86.6 13.3 N.A. 13.3 13.3 N.A. N.A. 26.6 13.3 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 40 N.A. 20 20 N.A. N.A. 40 33.3 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 24 39 0 0 0 0 8 0 0 0 0 % A
% Cys: 8 0 8 0 0 0 0 8 8 8 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 8 0 8 8 0 0 8 16 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 24 24 0 0 0 0 0 0 8 16 16 0 0 0 % G
% His: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 8 8 8 8 0 8 0 0 0 0 0 % I
% Lys: 8 0 16 8 8 16 8 0 0 0 16 8 54 8 0 % K
% Leu: 0 8 8 8 8 0 24 0 31 16 24 0 0 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 8 0 16 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 24 0 16 0 0 0 24 0 24 31 31 8 0 31 % P
% Gln: 16 0 0 0 16 0 24 0 0 0 0 0 0 8 0 % Q
% Arg: 39 24 8 8 8 0 24 0 0 31 0 24 16 62 16 % R
% Ser: 0 16 16 39 8 16 0 31 47 0 8 0 0 8 16 % S
% Thr: 8 0 8 0 8 0 0 8 0 0 0 16 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _