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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 9.39
Human Site: S255 Identified Species: 17.22
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S255 R T P V G Q G S W A H P G R T
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S255 R T P V G Q G S W A H P G R T
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S255 R T P V G Q G S W A H P D R T
Dog Lupus familis XP_851664 1092 121456 R239 V P L A K R P R R S V A S E P
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 A247 S V P S A K K A R C Y P V P R
Rat Rattus norvegicus Q673L6 1125 126915 A247 N V P S A K K A R F E P A L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 N420 A E K R A E S N R R G I E M Y
Frog Xenopus laevis NP_001079102 1191 137998 V303 N M Y P K T N V Q V T G L I T
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 C245 N G N Y R S L C F A I S K K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 R416 Y S P K V F Q R K R P K Q S V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 E293 K S L T S Q S E I S T N G F G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 H235 V G E D V D Q H R E K K T T K
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 T74 H C I I Y L L T G E L Y N N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 93.3 0 N.A. 13.3 13.3 N.A. N.A. 0 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 13.3 N.A. 33.3 26.6 N.A. N.A. 13.3 6.6 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 0 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 24 0 0 16 0 31 0 8 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 8 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 8 8 0 0 8 0 8 0 16 8 0 8 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 8 0 0 0 8 0 % F
% Gly: 0 16 0 0 24 0 24 0 8 0 8 8 24 0 8 % G
% His: 8 0 0 0 0 0 0 8 0 0 24 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 8 0 8 8 0 8 0 % I
% Lys: 8 0 8 8 16 16 16 0 8 0 8 16 8 8 8 % K
% Leu: 0 0 16 0 0 8 16 0 0 0 8 0 8 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 24 0 8 0 0 0 8 8 0 0 0 8 8 8 0 % N
% Pro: 0 8 47 8 0 0 8 0 0 0 8 39 0 8 8 % P
% Gln: 0 0 0 0 0 31 16 0 8 0 0 0 8 0 0 % Q
% Arg: 24 0 0 8 8 8 0 16 39 16 0 0 0 24 24 % R
% Ser: 8 16 0 16 8 8 16 24 0 16 0 8 8 8 0 % S
% Thr: 0 24 0 8 0 8 0 8 0 0 16 0 8 8 31 % T
% Val: 16 16 0 24 16 0 0 8 0 8 8 0 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % W
% Tyr: 8 0 8 8 8 0 0 0 0 0 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _