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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TERT
All Species:
37.88
Human Site:
S504
Identified Species:
69.44
UniProt:
O14746
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14746
NP_937983.2
1132
126997
S504
L
G
K
H
A
K
L
S
L
Q
E
L
T
W
K
Chimpanzee
Pan troglodytes
XP_001141663
1135
126922
S504
L
G
K
H
A
K
L
S
L
Q
E
L
T
W
K
Rhesus Macaque
Macaca mulatta
XP_001096904
1132
126842
S504
L
G
K
H
A
K
L
S
L
R
E
L
T
W
K
Dog
Lupus familis
XP_851664
1092
121456
S493
L
G
K
H
A
K
L
S
L
Q
E
L
T
W
K
Cat
Felis silvestris
Mouse
Mus musculus
O70372
1122
127960
S494
L
G
K
Y
G
K
L
S
L
Q
E
L
M
W
K
Rat
Rattus norvegicus
Q673L6
1125
126915
S494
L
G
K
Y
A
K
L
S
L
Q
E
L
M
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026178
1346
155264
S713
M
G
K
Y
A
K
L
S
L
Q
Q
L
M
W
K
Frog
Xenopus laevis
NP_001079102
1191
137998
S559
S
G
K
F
G
K
I
S
L
S
E
L
M
W
S
Zebra Danio
Brachydanio rerio
NP_001077335
1098
125968
T490
L
G
K
F
E
R
L
T
L
V
Q
L
M
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781093
1312
150053
S690
L
G
R
F
E
R
L
S
L
R
E
L
T
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105870
1188
135970
C562
L
R
R
F
E
S
F
C
L
S
D
C
I
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197187
1123
130561
T496
R
R
R
N
E
K
C
T
V
N
Q
F
L
H
K
Baker's Yeast
Sacchar. cerevisiae
Q06163
884
102645
L316
I
I
K
N
L
N
L
L
L
S
L
P
L
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
95.8
70.3
N.A.
63.3
63.3
N.A.
N.A.
45.2
42.9
32.8
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
97.9
97.4
77.5
N.A.
74
73.5
N.A.
N.A.
58.2
60.1
50.8
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
93.3
100
N.A.
80
80
N.A.
N.A.
73.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
93.3
60
73.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
24.7
N.A.
24.8
20.7
N.A.
Protein Similarity:
N.A.
40.4
N.A.
42.6
36.9
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
31
0
0
0
0
0
62
0
0
8
16
% E
% Phe:
0
0
0
31
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
77
0
0
16
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
31
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
77
0
0
70
0
0
0
0
0
0
0
0
54
% K
% Leu:
70
0
0
0
8
0
77
8
93
0
8
77
16
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% M
% Asn:
0
0
0
16
0
8
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
24
0
0
0
0
% Q
% Arg:
8
16
24
0
0
16
0
0
0
16
0
0
0
0
16
% R
% Ser:
8
0
0
0
0
8
0
70
0
24
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
39
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% W
% Tyr:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _