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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TERT
All Species:
14.55
Human Site:
S523
Identified Species:
26.67
UniProt:
O14746
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14746
NP_937983.2
1132
126997
S523
D
C
A
W
L
R
R
S
P
G
V
G
C
V
P
Chimpanzee
Pan troglodytes
XP_001141663
1135
126922
S523
D
C
A
W
L
R
R
S
P
G
V
G
S
V
P
Rhesus Macaque
Macaca mulatta
XP_001096904
1132
126842
S523
D
C
A
W
L
R
K
S
P
G
V
G
C
V
P
Dog
Lupus familis
XP_851664
1092
121456
N512
D
C
T
W
L
H
G
N
P
G
A
C
C
V
P
Cat
Felis silvestris
Mouse
Mus musculus
O70372
1122
127960
S513
D
C
H
W
L
R
S
S
P
G
K
D
R
V
P
Rat
Rattus norvegicus
Q673L6
1125
126915
S513
D
C
H
W
L
R
S
S
P
E
K
D
T
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026178
1346
155264
A732
D
C
V
W
L
R
L
A
K
G
N
H
S
V
P
Frog
Xenopus laevis
NP_001079102
1191
137998
Q578
D
C
S
W
I
R
L
Q
K
S
D
H
F
V
P
Zebra Danio
Brachydanio rerio
NP_001077335
1098
125968
K509
A
C
H
W
L
G
P
K
K
R
Q
C
A
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781093
1312
150053
E709
D
C
D
W
C
Q
L
E
K
F
R
G
R
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105870
1188
135970
I581
H
Y
S
W
L
S
N
I
G
F
S
D
C
F
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197187
1123
130561
K515
D
F
P
F
F
A
R
K
E
L
C
C
M
V
N
Baker's Yeast
Sacchar. cerevisiae
Q06163
884
102645
R335
D
S
L
L
K
K
L
R
L
K
D
F
R
W
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
95.8
70.3
N.A.
63.3
63.3
N.A.
N.A.
45.2
42.9
32.8
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
97.9
97.4
77.5
N.A.
74
73.5
N.A.
N.A.
58.2
60.1
50.8
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
93.3
93.3
60
N.A.
66.6
60
N.A.
N.A.
53.3
40
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
100
66.6
N.A.
66.6
60
N.A.
N.A.
60
53.3
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
24.7
N.A.
24.8
20.7
N.A.
Protein Similarity:
N.A.
40.4
N.A.
42.6
36.9
N.A.
P-Site Identity:
N.A.
20
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
0
0
8
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
77
0
0
8
0
0
0
0
0
8
24
31
0
8
% C
% Asp:
85
0
8
0
0
0
0
0
0
0
16
24
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
8
% E
% Phe:
0
8
0
8
8
0
0
0
0
16
0
8
8
8
0
% F
% Gly:
0
0
0
0
0
8
8
0
8
47
0
31
0
0
0
% G
% His:
8
0
24
0
0
8
0
0
0
0
0
16
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
8
8
16
31
8
16
0
0
0
0
% K
% Leu:
0
0
8
8
70
0
31
0
8
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
8
0
47
0
0
0
0
0
70
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
54
24
8
0
8
8
0
24
0
0
% R
% Ser:
0
8
16
0
0
8
16
39
0
8
8
0
16
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
24
0
0
70
0
% V
% Trp:
0
0
0
85
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _