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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 29.7
Human Site: S579 Identified Species: 54.44
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S579 R L F F Y R K S V W S K L Q S
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S579 R L F F Y R K S V W S K L Q S
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S579 R L F F Y R K S V W S K L Q S
Dog Lupus familis XP_851664 1092 121456 S568 R L F F Y R K S V W S Q L Q S
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 S569 R L F F Y R K S V W S K L Q S
Rat Rattus norvegicus Q673L6 1125 126915 S569 R L F F Y R K S V W S K L Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 F788 M L F Y Y R K F I W G K L Q N
Frog Xenopus laevis NP_001079102 1191 137998 S634 R L L F Y R K S V W K K L Q N
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 H554 T E S M G H K H T L R F Y R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 P766 Q L V F Y R K P V W L L L E K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 S629 I V I P L V Q S Y F Y V T E R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 F559 K K L V H F N F Y A T E S Q G
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 T379 L I P K I I Q T F F Y C T E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 60 80 6.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 80 86.6 13.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 8 0 24 0 % E
% Phe: 0 0 54 62 0 8 0 16 8 16 0 8 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 16 % G
% His: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 8 8 0 0 8 0 0 0 0 0 8 % I
% Lys: 8 8 0 8 0 0 77 0 0 0 8 54 0 0 8 % K
% Leu: 8 70 16 0 8 0 0 0 0 8 8 8 70 0 0 % L
% Met: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 16 % N
% Pro: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 16 0 0 0 0 8 0 70 0 % Q
% Arg: 54 0 0 0 0 70 0 0 0 0 8 0 0 8 8 % R
% Ser: 0 0 8 0 0 0 0 62 0 0 47 0 8 0 47 % S
% Thr: 8 0 0 0 0 0 0 8 8 0 8 0 16 0 0 % T
% Val: 0 8 8 8 0 8 0 0 62 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % W
% Tyr: 0 0 0 8 70 0 0 0 16 0 16 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _