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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 21.52
Human Site: S656 Identified Species: 39.44
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S656 K R A E R L T S R V K A L F S
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S656 K R A E R L T S R V K A L F S
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S656 K R A E R L A S R V K A L F S
Dog Lupus familis XP_851664 1092 121456 S645 K K V Q H L T S Q L K T L F S
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 Q646 K Q A Q H F T Q R L K T L F S
Rat Rattus norvegicus Q673L6 1125 126915 Q646 K Q T Q C F T Q S L K T L F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 T868 K K I Q R Y N T Q L K N L F S
Frog Xenopus laevis NP_001079102 1191 137998 S713 K K I H H F S S Q I R N L F S
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 S628 D T L Q Y F Q S C V R V L Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 L838 K K G L S V R L L L Q D L F D
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 A709 L R A Q S K N A L L N N C H L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 S635 S S S S R S Q S L R D T H A V
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 R450 K K S N N E F R I I A I P C R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 93.3 53.3 N.A. 53.3 40 N.A. N.A. 40 33.3 20 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 80 N.A. 73.3 60 N.A. N.A. 73.3 66.6 40 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 33.3 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 39 0 0 0 8 8 0 0 8 24 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 0 0 8 8 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % D
% Glu: 0 0 0 24 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 31 8 0 0 0 0 0 0 70 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 24 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 16 0 0 0 0 0 8 16 0 8 0 0 0 % I
% Lys: 77 39 0 0 0 8 0 0 0 0 54 0 0 0 0 % K
% Leu: 8 0 8 8 0 31 0 8 24 47 0 0 77 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 16 0 0 0 8 24 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 16 0 47 0 0 16 16 24 0 8 0 0 8 0 % Q
% Arg: 0 31 0 0 39 0 8 8 31 8 16 0 0 0 8 % R
% Ser: 8 8 16 8 16 8 8 54 8 0 0 0 0 0 62 % S
% Thr: 0 8 8 0 0 0 39 8 0 0 0 31 0 0 0 % T
% Val: 0 0 8 0 0 8 0 0 0 31 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _