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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 19.7
Human Site: S70 Identified Species: 36.11
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 S70 R P P P A A P S F R Q V S C L
Chimpanzee Pan troglodytes XP_001141663 1135 126922 S70 R P P P A A P S F R Q V S C L
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 S70 R P P P A A P S F R Q V S C L
Dog Lupus familis XP_851664 1092 121456 C70 R P P P A A P C F R Q V S C L
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 S70 Q P P P A D L S F H Q V S S L
Rat Rattus norvegicus Q673L6 1125 126915 S70 Q P P P A D L S F H Q V S S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 C89 R A I P R P I C F Q Q L S S Q
Frog Xenopus laevis NP_001079102 1191 137998 S73 K P L P S P V S F L Q L S T Q
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 V73 Y T P P Q L R V P A Q L S T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 I154 A A P P S C Y I Q L T G T P L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 P100 T P P P L Y T P G N G G H S Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 S63 K P A F L L R S D D P I H Y R
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 93.3 N.A. 66.6 66.6 N.A. N.A. 33.3 40 33.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. N.A. 46.6 60 40 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 20 N.A. 13.3 0 N.A.
P-Site Similarity: N.A. 20 N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 47 31 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 16 0 0 0 0 0 31 0 % C
% Asp: 0 0 0 0 0 16 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 62 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 8 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 16 0 0 16 0 0 % H
% Ile: 0 0 8 0 0 0 8 8 0 0 0 8 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 16 16 16 0 0 16 0 24 0 0 62 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 70 70 85 0 16 31 8 8 0 8 0 0 8 0 % P
% Gln: 16 0 0 0 8 0 0 0 8 8 70 0 0 0 24 % Q
% Arg: 39 0 0 0 8 0 16 0 0 31 0 0 0 0 8 % R
% Ser: 0 0 0 0 16 0 0 54 0 0 0 0 70 31 0 % S
% Thr: 8 8 0 0 0 0 8 0 0 0 8 0 8 16 0 % T
% Val: 0 0 0 0 0 0 8 8 0 0 0 47 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _