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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 11.52
Human Site: T319 Identified Species: 21.11
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 T319 R P P R P W D T P C P P V Y A
Chimpanzee Pan troglodytes XP_001141663 1135 126922 T319 R P P R P W D T P C P P V Y A
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 T319 R P P S P W D T R C P L V Y A
Dog Lupus familis XP_851664 1092 121456 V303 P S P G P Q G V P H D P A H P
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 S311 V C C K H K P S S T S L L S P
Rat Rattus norvegicus Q673L6 1125 126915 S311 V C C K H K P S S S S L L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 L484 A K Q L P N T L S R S T V Y F
Frog Xenopus laevis NP_001079102 1191 137998 S367 P T A Q S R L S F S N I F I D
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 E309 L K R Q R M E E I D Q V A K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 T480 M E M D E N A T S S T A D D A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 M357 Q V G L P N F M H L N N G L I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 K299 G S L T D F V K Q A K Q V K R
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 Q138 L I N Y T V I Q F N G Q F F T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 80 26.6 N.A. 0 0 N.A. N.A. 20 0 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 80 33.3 N.A. 20 26.6 N.A. N.A. 20 13.3 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 8 0 0 8 0 8 16 0 31 % A
% Cys: 0 16 16 0 0 0 0 0 0 24 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 24 0 0 8 8 0 8 8 8 % D
% Glu: 0 8 0 0 8 0 8 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 16 0 0 0 16 8 8 % F
% Gly: 8 0 8 8 0 0 8 0 0 0 8 0 8 0 0 % G
% His: 0 0 0 0 16 0 0 0 8 8 0 0 0 8 0 % H
% Ile: 0 8 0 0 0 0 8 0 8 0 0 8 0 8 16 % I
% Lys: 0 16 0 16 0 16 0 8 0 0 8 0 0 16 0 % K
% Leu: 16 0 8 16 0 0 8 8 0 8 0 24 16 8 0 % L
% Met: 8 0 8 0 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 24 0 0 0 8 16 8 0 0 0 % N
% Pro: 16 24 31 0 47 0 16 0 24 0 24 24 0 0 16 % P
% Gln: 8 0 8 16 0 8 0 8 8 0 8 16 0 0 0 % Q
% Arg: 24 0 8 16 8 8 0 0 8 8 0 0 0 0 8 % R
% Ser: 0 16 0 8 8 0 0 24 31 24 24 0 0 16 8 % S
% Thr: 0 8 0 8 8 0 8 31 0 8 8 8 0 0 8 % T
% Val: 16 8 0 0 0 8 8 8 0 0 0 8 39 0 0 % V
% Trp: 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 31 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _