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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TERT
All Species:
10.3
Human Site:
T375
Identified Species:
18.89
UniProt:
O14746
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14746
NP_937983.2
1132
126997
T375
S
R
P
W
M
P
G
T
P
R
R
L
P
R
L
Chimpanzee
Pan troglodytes
XP_001141663
1135
126922
T375
S
R
P
W
M
P
G
T
P
R
R
L
P
R
L
Rhesus Macaque
Macaca mulatta
XP_001096904
1132
126842
T375
S
R
P
W
M
P
G
T
P
R
R
P
P
R
L
Dog
Lupus familis
XP_851664
1092
121456
A359
S
A
P
Q
K
P
G
A
A
R
R
M
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O70372
1122
127960
E367
T
G
A
R
R
L
V
E
I
I
F
L
G
S
R
Rat
Rattus norvegicus
Q673L6
1125
126915
E367
T
G
A
R
R
L
V
E
I
I
F
L
G
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026178
1346
155264
Q540
Q
N
P
L
K
E
Q
Q
N
Q
S
L
P
Q
Q
Frog
Xenopus laevis
NP_001079102
1191
137998
F423
N
F
L
A
E
Q
N
F
D
Q
P
K
R
D
E
Zebra Danio
Brachydanio rerio
NP_001077335
1098
125968
V365
L
N
R
K
L
K
G
V
G
G
A
R
R
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781093
1312
150053
S536
D
D
D
T
L
T
V
S
G
K
I
L
S
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105870
1188
135970
A413
N
K
R
K
I
P
D
A
L
S
L
I
I
H
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197187
1123
130561
P355
V
N
V
W
S
T
T
P
S
H
G
K
G
N
C
Baker's Yeast
Sacchar. cerevisiae
Q06163
884
102645
N194
F
L
H
K
L
N
I
N
S
S
S
F
F
P
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
95.8
70.3
N.A.
63.3
63.3
N.A.
N.A.
45.2
42.9
32.8
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
97.9
97.4
77.5
N.A.
74
73.5
N.A.
N.A.
58.2
60.1
50.8
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
93.3
53.3
N.A.
6.6
6.6
N.A.
N.A.
20
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
60
N.A.
13.3
13.3
N.A.
N.A.
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
24.7
N.A.
24.8
20.7
N.A.
Protein Similarity:
N.A.
40.4
N.A.
42.6
36.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
40
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
0
16
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
8
0
0
0
8
0
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
8
0
16
0
0
0
0
0
0
8
% E
% Phe:
8
8
0
0
0
0
0
8
0
0
16
8
8
0
0
% F
% Gly:
0
16
0
0
0
0
39
0
16
8
8
0
24
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
8
0
16
16
8
8
8
0
8
% I
% Lys:
0
8
0
24
16
8
0
0
0
8
0
16
0
0
0
% K
% Leu:
8
8
8
8
24
16
0
0
8
0
8
47
0
0
31
% L
% Met:
0
0
0
0
24
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
16
24
0
0
0
8
8
8
8
0
0
0
0
8
0
% N
% Pro:
0
0
39
0
0
39
0
8
24
0
8
8
31
8
8
% P
% Gln:
8
0
0
8
0
8
8
8
0
16
0
0
0
16
16
% Q
% Arg:
0
24
16
16
16
0
0
0
0
31
31
8
24
31
16
% R
% Ser:
31
0
0
0
8
0
0
8
16
16
16
0
8
16
0
% S
% Thr:
16
0
0
8
0
16
8
24
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
24
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _