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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 14.55
Human Site: T644 Identified Species: 26.67
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 T644 D Y V V G A R T F R R E K R A
Chimpanzee Pan troglodytes XP_001141663 1135 126922 T644 D Y V V G A R T F R R E K R A
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 T644 D Y V V G A R T F R R E K R A
Dog Lupus familis XP_851664 1092 121456 T633 D Y I M G A R T F H R D K K V
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 A634 S Y S M G T R A L G R R K Q A
Rat Rattus norvegicus Q673L6 1125 126915 A634 S Y G M D T R A F G K K K Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 K856 V E G Q K L S K E S R E K K I
Frog Xenopus laevis NP_001079102 1191 137998 K701 T L S S Q Q S K E N Q E K K I
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 L616 S M R P I T R L S G S R D T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 S826 P I T R M G K S V I E E K K G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 R697 I P K A K D M R P L V N L R A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 M623 P K A N G V R M V L D F S S S
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 M438 S N F N H S K M R I I P K K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 60 N.A. 40 26.6 N.A. N.A. 20 13.3 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 53.3 53.3 N.A. N.A. 26.6 26.6 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 31 0 16 0 0 0 0 0 0 39 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 31 0 0 0 8 8 0 0 0 0 8 8 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 16 0 8 47 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 39 0 0 8 0 0 0 % F
% Gly: 0 0 16 0 47 8 0 0 0 24 0 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 8 8 0 8 0 0 0 0 16 8 0 0 0 16 % I
% Lys: 0 8 8 0 16 0 16 16 0 0 8 8 77 39 0 % K
% Leu: 0 8 0 0 0 8 0 8 8 16 0 0 8 0 8 % L
% Met: 0 8 0 24 8 0 8 16 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 16 0 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 16 8 0 8 0 0 0 0 8 0 0 8 0 0 0 % P
% Gln: 0 0 0 8 8 8 0 0 0 0 8 0 0 16 0 % Q
% Arg: 0 0 8 8 0 0 62 8 8 24 47 16 0 31 0 % R
% Ser: 31 0 16 8 0 8 16 8 8 8 8 0 8 8 16 % S
% Thr: 8 0 8 0 0 24 0 31 0 0 0 0 0 8 8 % T
% Val: 8 0 24 24 0 8 0 0 16 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _