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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TERT
All Species:
6.97
Human Site:
Y744
Identified Species:
12.78
UniProt:
O14746
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14746
NP_937983.2
1132
126997
Y744
N
T
Y
C
V
R
R
Y
A
V
V
Q
K
A
A
Chimpanzee
Pan troglodytes
XP_001141663
1135
126922
N744
N
T
Y
L
I
G
R
N
K
C
P
A
L
A
G
Rhesus Macaque
Macaca mulatta
XP_001096904
1132
126842
Y744
N
T
Y
C
V
R
R
Y
A
V
V
R
K
A
A
Dog
Lupus familis
XP_851664
1092
121456
H733
E
S
T
Y
C
V
R
H
Y
A
V
V
Q
R
T
Cat
Felis silvestris
Mouse
Mus musculus
O70372
1122
127960
Q734
E
S
T
Y
C
I
R
Q
Y
A
V
V
R
R
D
Rat
Rattus norvegicus
Q673L6
1125
126915
Q734
E
S
M
Y
C
I
R
Q
Y
A
V
V
Q
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026178
1346
155264
I956
E
S
Q
T
V
Y
G
I
R
W
Y
A
V
I
M
Frog
Xenopus laevis
NP_001079102
1191
137998
I801
N
A
N
E
V
Y
C
I
R
R
Y
A
T
V
S
Zebra Danio
Brachydanio rerio
NP_001077335
1098
125968
Y716
Q
S
F
F
L
R
Q
Y
S
S
V
W
S
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781093
1312
150053
L926
D
K
P
D
E
Y
Q
L
Q
R
Y
V
T
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105870
1188
135970
C797
D
D
Y
V
L
R
K
C
K
K
V
V
C
N
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197187
1123
130561
L723
Y
I
L
N
R
C
R
L
V
C
C
G
K
R
S
Baker's Yeast
Sacchar. cerevisiae
Q06163
884
102645
I538
V
K
S
C
Y
D
S
I
P
R
M
E
C
M
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
95.8
70.3
N.A.
63.3
63.3
N.A.
N.A.
45.2
42.9
32.8
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
97.9
97.4
77.5
N.A.
74
73.5
N.A.
N.A.
58.2
60.1
50.8
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
33.3
93.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
40
100
33.3
N.A.
26.6
26.6
N.A.
N.A.
13.3
20
53.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
24.7
N.A.
24.8
20.7
N.A.
Protein Similarity:
N.A.
40.4
N.A.
42.6
36.9
N.A.
P-Site Identity:
N.A.
20
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
16
24
0
24
0
24
16
% A
% Cys:
0
0
0
24
24
8
8
8
0
16
8
0
16
0
0
% C
% Asp:
16
8
0
8
0
8
0
0
0
0
0
0
0
8
16
% D
% Glu:
31
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
16
0
24
0
0
0
0
0
8
0
% I
% Lys:
0
16
0
0
0
0
8
0
16
8
0
0
24
8
0
% K
% Leu:
0
0
8
8
16
0
0
16
0
0
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
8
% M
% Asn:
31
0
8
8
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
8
% P
% Gln:
8
0
8
0
0
0
16
16
8
0
0
8
16
0
0
% Q
% Arg:
0
0
0
0
8
31
54
0
16
24
0
8
8
24
8
% R
% Ser:
0
39
8
0
0
0
8
0
8
8
0
0
8
0
16
% S
% Thr:
0
24
16
8
0
0
0
0
0
0
0
0
16
0
16
% T
% Val:
8
0
0
8
31
8
0
0
8
16
54
39
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% W
% Tyr:
8
0
31
24
8
24
0
24
24
0
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _