KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GABRD
All Species:
21.21
Human Site:
T371
Identified Species:
51.85
UniProt:
O14764
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14764
NP_000806.2
452
50708
T371
S
L
S
A
A
G
V
T
Q
E
L
A
I
S
R
Chimpanzee
Pan troglodytes
XP_001156161
428
48116
T347
S
L
S
A
A
G
V
T
Q
E
L
A
I
S
R
Rhesus Macaque
Macaca mulatta
XP_001108947
474
54445
H376
L
L
T
S
L
E
V
H
N
E
M
N
E
V
A
Dog
Lupus familis
XP_546729
432
48748
T351
S
L
S
A
A
G
V
T
Q
E
L
A
V
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P22933
449
50504
S371
S
L
S
A
A
G
V
S
Q
E
L
A
I
S
R
Rat
Rattus norvegicus
P18506
449
50548
S371
S
L
S
A
A
G
V
S
Q
E
L
A
I
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505697
468
53685
T363
S
R
G
N
I
L
L
T
S
L
E
I
H
N
E
Chicken
Gallus gallus
P19019
476
54414
S396
D
A
R
N
S
T
I
S
F
D
N
S
G
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O93430
444
50747
P367
F
A
A
Y
G
M
G
P
A
C
L
Q
A
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08832
496
56579
L382
T
T
E
D
I
I
E
L
Q
D
V
R
M
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
40.7
87.1
N.A.
92
92.4
N.A.
42
40.3
N.A.
34
N.A.
37.7
N.A.
N.A.
N.A.
Protein Similarity:
100
94.6
60.1
90.2
N.A.
94.6
94.9
N.A.
61.1
58.8
N.A.
51.9
N.A.
56
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
13.3
0
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
26.6
40
N.A.
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
50
50
0
0
0
10
0
0
50
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
20
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
10
10
0
0
60
10
0
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
50
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
20
10
10
0
0
0
0
10
40
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
60
0
0
10
10
10
10
0
10
60
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
20
0
0
0
0
10
0
10
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
60
0
0
10
0
0
10
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
50
% R
% Ser:
60
0
50
10
10
0
0
30
10
0
0
10
0
60
0
% S
% Thr:
10
10
10
0
0
10
0
40
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
60
0
0
0
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _