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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS2
All Species:
13.64
Human Site:
S453
Identified Species:
30
UniProt:
O14770
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14770
NP_733774.1
477
51790
S453
T
H
P
G
M
T
M
S
A
Q
S
P
T
M
L
Chimpanzee
Pan troglodytes
XP_001166966
466
50898
A443
H
P
G
M
P
M
S
A
S
S
P
T
V
L
N
Rhesus Macaque
Macaca mulatta
XP_001092777
477
52057
A454
H
P
G
M
P
M
S
A
S
S
P
T
V
L
N
Dog
Lupus familis
XP_848817
477
51723
S453
T
H
P
G
M
T
M
S
A
Q
S
P
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P97367
477
51709
S453
T
H
P
G
M
T
M
S
A
Q
S
P
T
M
L
Rat
Rattus norvegicus
NP_001101228
470
50965
S446
T
H
P
G
M
T
M
S
A
Q
S
P
T
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990134
401
43788
M385
G
I
R
P
A
G
P
M
S
G
M
G
M
N
M
Frog
Xenopus laevis
Q5U4X3
453
49097
Q436
P
H
H
L
V
S
A
Q
S
P
A
D
A
L
L
Zebra Danio
Brachydanio rerio
NP_571971
397
43562
P380
M
G
I
R
P
A
G
P
M
S
G
M
G
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
M454
H
D
A
M
G
Y
M
M
D
S
Q
A
H
M
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
P535
S
F
T
N
P
A
M
P
F
M
N
P
M
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.8
83
99.5
N.A.
99.5
97.9
N.A.
N.A.
82.3
68.9
79.6
N.A.
36.7
N.A.
28.5
N.A.
Protein Similarity:
100
88.6
89.5
100
N.A.
99.7
98.3
N.A.
N.A.
82.8
77.5
80.7
N.A.
49
N.A.
41.3
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
100
100
N.A.
N.A.
0
13.3
6.6
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
N.A.
13.3
46.6
6.6
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
19
10
19
37
0
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
19
37
10
10
10
0
0
10
10
10
10
0
10
% G
% His:
28
46
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
28
46
% L
% Met:
10
0
0
28
37
19
55
19
10
10
10
10
19
55
19
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
28
% N
% Pro:
10
19
37
10
37
0
10
19
0
10
19
46
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
37
10
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
19
37
37
37
37
0
0
0
0
% S
% Thr:
37
0
10
0
0
37
0
0
0
0
0
19
37
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _