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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FPGT All Species: 8.48
Human Site: S374 Identified Species: 23.33
UniProt: O14772 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14772 NP_003829.2 594 66599 S374 F Y F T S D N S L K S E L G L
Chimpanzee Pan troglodytes XP_513493 949 105567 S490 V A C D P S R S S G E K D E Q
Rhesus Macaque Macaca mulatta XP_001097254 949 105560 S490 V A C D P S R S S G E K D E Q
Dog Lupus familis XP_537112 1087 119299 S645 V A C D P S R S S G E K D E Q
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus NP_955788 591 65993 T366 L H F T S D S T L R S R A R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422544 886 98029 S465 V A C D P S R S S G E K D E Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018590 532 59132 C313 F H L T A D P C L R A E L G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001076643 395 44628 R175 F V M D K K T R K L K R V L Q
Sea Urchin Strong. purpuratus XP_001197589 595 66215 S364 S H F C D N C S L R R E L S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.8 26.9 22.1 N.A. N.A. 72.2 N.A. N.A. 22.5 N.A. 51 N.A. N.A. N.A. 23.3 39.5
Protein Similarity: 100 38.9 38.9 32.9 N.A. N.A. 83.3 N.A. N.A. 36.1 N.A. 67.5 N.A. N.A. N.A. 38.8 57.4
P-Site Identity: 100 6.6 6.6 6.6 N.A. N.A. 46.6 N.A. N.A. 6.6 N.A. 53.3 N.A. N.A. N.A. 6.6 40
P-Site Similarity: 100 13.3 13.3 13.3 N.A. N.A. 73.3 N.A. N.A. 13.3 N.A. 80 N.A. N.A. N.A. 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 0 0 12 0 0 0 0 0 12 0 12 0 0 % A
% Cys: 0 0 45 12 0 0 12 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 56 12 34 0 0 0 0 0 0 45 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 45 34 0 45 0 % E
% Phe: 34 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 45 0 0 0 23 0 % G
% His: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 12 12 0 0 12 12 12 45 0 0 0 % K
% Leu: 12 0 12 0 0 0 0 0 45 12 0 0 34 12 45 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 45 0 12 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 % Q
% Arg: 0 0 0 0 0 0 45 12 0 34 12 23 0 12 0 % R
% Ser: 12 0 0 0 23 45 12 67 45 0 23 0 0 12 0 % S
% Thr: 0 0 0 34 0 0 12 12 0 0 0 0 0 0 0 % T
% Val: 45 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _