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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FPGT All Species: 4.24
Human Site: S514 Identified Species: 11.67
UniProt: O14772 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14772 NP_003829.2 594 66599 S514 K V T E E L F S G N K T C L S
Chimpanzee Pan troglodytes XP_513493 949 105567 L630 E V S I L C Q L N H P C V I Q
Rhesus Macaque Macaca mulatta XP_001097254 949 105560 L630 E V S I L C Q L N H P C V I Q
Dog Lupus familis XP_537112 1087 119299 L785 E V S I L C R L N H P C I I Q
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus NP_955788 591 65993 S506 K A T E K L F S G S K R N L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422544 886 98029 L605 E V S I L C R L N H P C V I Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018590 532 59132 S453 V R F S G D A S V C S L W N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001076643 395 44628 I315 P G A F K S N I V F S N G I S
Sea Urchin Strong. purpuratus XP_001197589 595 66215 F504 N Q S L Q V L F N N F N S T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.8 26.9 22.1 N.A. N.A. 72.2 N.A. N.A. 22.5 N.A. 51 N.A. N.A. N.A. 23.3 39.5
Protein Similarity: 100 38.9 38.9 32.9 N.A. N.A. 83.3 N.A. N.A. 36.1 N.A. 67.5 N.A. N.A. N.A. 38.8 57.4
P-Site Identity: 100 6.6 6.6 6.6 N.A. N.A. 66.6 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 33.3 33.3 33.3 N.A. N.A. 80 N.A. N.A. 33.3 N.A. 13.3 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 0 0 12 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 45 0 0 0 12 0 45 12 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 45 0 0 23 12 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 12 0 0 23 12 0 12 12 0 0 0 0 % F
% Gly: 0 12 0 0 12 0 0 0 23 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % H
% Ile: 0 0 0 45 0 0 0 12 0 0 0 0 12 56 0 % I
% Lys: 23 0 0 0 23 0 0 0 0 0 23 0 0 0 0 % K
% Leu: 0 0 0 12 45 23 12 45 0 0 0 12 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 12 0 56 23 0 23 12 12 0 % N
% Pro: 12 0 0 0 0 0 0 0 0 0 45 0 0 0 0 % P
% Gln: 0 12 0 0 12 0 23 0 0 0 0 0 0 0 45 % Q
% Arg: 0 12 0 0 0 0 23 0 0 0 0 12 0 0 0 % R
% Ser: 0 0 56 12 0 12 0 34 0 12 23 0 12 0 45 % S
% Thr: 0 0 23 0 0 0 0 0 0 0 0 12 0 12 0 % T
% Val: 12 56 0 0 0 12 0 0 23 0 0 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _