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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP1
All Species:
13.33
Human Site:
S495
Identified Species:
41.9
UniProt:
O14773
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14773
NP_000382.3
563
61248
S495
I
N
E
H
R
I
L
S
G
R
P
P
L
G
F
Chimpanzee
Pan troglodytes
Q5IS74
563
61277
S495
I
N
E
H
R
I
L
S
G
R
P
P
L
G
F
Rhesus Macaque
Macaca mulatta
XP_001108748
572
62256
S504
I
N
E
H
R
I
L
S
G
R
P
P
L
G
F
Dog
Lupus familis
XP_855613
563
61316
S495
I
N
E
H
R
L
L
S
G
L
P
P
L
G
F
Cat
Felis silvestris
Mouse
Mus musculus
O89023
562
61324
N494
I
N
E
H
R
I
L
N
G
R
P
P
L
G
F
Rat
Rattus norvegicus
Q9EQV6
563
61314
N495
I
N
E
H
R
L
L
N
G
R
P
P
L
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084555
566
62519
K496
I
N
D
R
R
L
Q
K
G
L
S
P
L
G
F
Zebra Danio
Brachydanio rerio
NP_001122270
557
61520
K490
I
N
D
Q
R
F
L
K
G
L
P
A
L
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
89.6
N.A.
88
87.7
N.A.
N.A.
N.A.
61.1
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97.5
94.3
N.A.
94.8
94.8
N.A.
N.A.
N.A.
76.8
76.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
100
0
% G
% His:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
38
88
0
0
38
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
100
0
0
0
0
0
25
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
88
88
0
0
0
% P
% Gln:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
100
0
0
0
0
63
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
13
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _