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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB5
All Species:
32.73
Human Site:
S123
Identified Species:
45
UniProt:
O14775
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14775
NP_006569.1
395
43566
S123
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
Chimpanzee
Pan troglodytes
XP_001151191
271
29444
Rhesus Macaque
Macaca mulatta
XP_001085617
398
43946
T126
S
K
K
D
L
L
F
T
C
Q
D
G
K
V
I
Dog
Lupus familis
XP_851178
395
43521
S123
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
Cat
Felis silvestris
Mouse
Mus musculus
P62881
395
43547
S123
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
Rat
Rattus norvegicus
P62882
353
38713
Q83
R
R
I
V
S
S
S
Q
D
G
K
V
I
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511953
185
20110
Chicken
Gallus gallus
XP_413801
395
43545
S123
D
K
R
R
I
V
S
S
S
Q
D
G
K
V
I
Frog
Xenopus laevis
P79959
340
37311
L70
W
G
T
D
S
R
L
L
V
S
A
S
Q
D
G
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
L70
W
G
T
D
S
R
L
L
V
S
A
S
Q
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
L70
W
G
N
D
S
R
N
L
V
S
A
S
Q
D
G
Honey Bee
Apis mellifera
XP_392638
349
38388
S79
D
K
R
H
I
V
S
S
S
Q
D
G
K
M
I
Nematode Worm
Caenorhab. elegans
Q20636
356
39435
S86
D
K
R
H
I
V
S
S
S
Q
D
G
K
V
I
Sea Urchin
Strong. purpuratus
XP_792481
354
39270
S83
D
Q
R
H
M
V
T
S
S
Q
D
G
K
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
S98
I
V
W
N
A
L
T
S
Q
K
T
H
A
I
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
S97
I
V
W
N
A
L
T
S
Q
K
T
H
A
I
K
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
A110
D
S
K
R
I
L
S
A
S
Q
D
G
F
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
91.2
97.7
N.A.
99.2
88.8
N.A.
45.5
94.9
46.3
46.8
N.A.
46.5
62.2
57.9
63.5
Protein Similarity:
100
68.6
93.9
98.2
N.A.
100
89.3
N.A.
46.8
97.4
63
63.5
N.A.
61.7
74.9
72.4
78.2
P-Site Identity:
100
0
46.6
100
N.A.
100
13.3
N.A.
0
100
0
0
N.A.
0
86.6
93.3
73.3
P-Site Similarity:
100
0
73.3
100
N.A.
100
20
N.A.
0
100
6.6
6.6
N.A.
13.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
37.7
N.A.
38.9
34.7
N.A.
Protein Similarity:
N.A.
58.7
N.A.
58.7
55.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
6
0
0
18
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
48
0
0
24
0
0
0
0
6
0
53
0
0
18
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
6
0
0
0
0
0
6
0
0
% F
% Gly:
0
18
0
0
0
0
0
0
0
6
0
53
0
0
18
% G
% His:
0
0
0
18
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
12
0
6
0
42
0
0
0
0
0
0
0
6
12
48
% I
% Lys:
0
42
12
0
0
0
0
0
0
12
6
0
48
0
12
% K
% Leu:
0
0
0
0
6
24
12
18
0
0
0
0
0
0
6
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
6
12
0
0
6
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
0
0
0
0
0
6
12
53
0
0
18
0
0
% Q
% Arg:
6
6
42
30
0
18
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
6
0
0
24
6
48
53
48
18
0
18
0
0
0
% S
% Thr:
0
0
12
0
0
0
18
6
0
0
12
0
0
0
0
% T
% Val:
0
12
0
6
0
42
0
0
18
0
0
6
0
48
0
% V
% Trp:
18
0
12
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _