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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNB5 All Species: 19.09
Human Site: T53 Identified Species: 26.25
UniProt: O14775 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14775 NP_006569.1 395 43566 T53 E G L H E N E T L A S L K S E
Chimpanzee Pan troglodytes XP_001151191 271 29444
Rhesus Macaque Macaca mulatta XP_001085617 398 43946 T53 E A L H E N E T L A S L K S E
Dog Lupus familis XP_851178 395 43521 T53 Q S S P E N Q T L A S L L S E
Cat Felis silvestris
Mouse Mus musculus P62881 395 43547 T53 D G L H E N E T L A S L K S E
Rat Rattus norvegicus P62882 353 38713 H39 K L H D V E L H Q V A E R V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511953 185 20110
Chicken Gallus gallus XP_413801 395 43545 T53 E G L H E N E T L A S L K N E
Frog Xenopus laevis P79959 340 37311 A26 R D A R K A C A D A T L A Q I
Zebra Danio Brachydanio rerio Q6PH57 340 37267 A26 R D A R K A C A D A T L S Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26308 340 37114 C26 R D A R K A A C D T S L L Q A
Honey Bee Apis mellifera XP_392638 349 38388 T35 R Q K L N D I T L A S V A D R
Nematode Worm Caenorhab. elegans Q20636 356 39435 P42 R H K L N D I P I Q Q A A E R
Sea Urchin Strong. purpuratus XP_792481 354 39270 E39 R H K L N D V E M Y T V A Q R
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 F51 Q G R V P V S F N P T D L V C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 T53 T R V S F G A T D L V C C R T
Baker's Yeast Sacchar. cerevisiae P18851 423 46563 K55 Q L H A Q I N K A K H K I Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.6 91.2 97.7 N.A. 99.2 88.8 N.A. 45.5 94.9 46.3 46.8 N.A. 46.5 62.2 57.9 63.5
Protein Similarity: 100 68.6 93.9 98.2 N.A. 100 89.3 N.A. 46.8 97.4 63 63.5 N.A. 61.7 74.9 72.4 78.2
P-Site Identity: 100 0 93.3 60 N.A. 93.3 6.6 N.A. 0 93.3 13.3 13.3 N.A. 13.3 26.6 0 0
P-Site Similarity: 100 0 93.3 73.3 N.A. 100 26.6 N.A. 0 100 26.6 26.6 N.A. 20 40 13.3 26.6
Percent
Protein Identity: N.A. 37.7 N.A. 38.9 34.7 N.A.
Protein Similarity: N.A. 58.7 N.A. 58.7 55.7 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 18 6 0 18 12 12 6 48 6 6 24 0 6 % A
% Cys: 0 0 0 0 0 0 12 6 0 0 0 6 6 0 6 % C
% Asp: 6 18 0 6 0 18 0 0 24 0 0 6 0 6 6 % D
% Glu: 18 0 0 0 30 6 24 6 0 0 0 6 0 6 36 % E
% Phe: 0 0 0 0 6 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 24 0 0 0 6 0 0 0 0 0 0 0 0 0 % G
% His: 0 12 12 24 0 0 0 6 0 0 6 0 0 0 0 % H
% Ile: 0 0 0 0 0 6 12 0 6 0 0 0 6 0 12 % I
% Lys: 6 0 18 0 18 0 0 6 0 6 0 6 24 0 0 % K
% Leu: 0 12 24 18 0 0 6 0 36 6 0 48 18 0 0 % L
% Met: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 18 30 6 0 6 0 0 0 0 6 0 % N
% Pro: 0 0 0 6 6 0 0 6 0 6 0 0 0 0 0 % P
% Gln: 18 6 0 0 6 0 6 0 6 6 6 0 0 30 0 % Q
% Arg: 36 6 6 18 0 0 0 0 0 0 0 0 6 6 18 % R
% Ser: 0 6 6 6 0 0 6 0 0 0 42 0 6 24 0 % S
% Thr: 6 0 0 0 0 0 0 42 0 6 24 0 0 0 6 % T
% Val: 0 0 6 6 6 6 6 0 0 6 6 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _