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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDC80 All Species: 29.7
Human Site: S116 Identified Species: 50.26
UniProt: O14777 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14777 NP_006092.1 642 73913 S116 A H N V S M K S L Q A P S V K
Chimpanzee Pan troglodytes XP_512046 642 73980 S116 A H N V S M K S L Q A P S V K
Rhesus Macaque Macaca mulatta XP_001086615 642 73921 S116 A H N V S M K S L Q A P S V K
Dog Lupus familis XP_537313 642 73907 S116 A Y S V S M K S L Q A P S V K
Cat Felis silvestris
Mouse Mus musculus Q9D0F1 642 73943 S116 V Y S V S M K S L Q A P S T K
Rat Rattus norvegicus NP_001119742 329 38011
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505423 649 75199 S118 A F N V S M K S L Q A P S V K
Chicken Gallus gallus Q76I89 640 73723 S119 A H N V T I K S L Q S P S V K
Frog Xenopus laevis Q8AWF5 638 74459 S115 S Q A L T V K S L Q G P S T K
Zebra Danio Brachydanio rerio Q6DRJ7 632 73198 A114 P G S I T V K A L Q S P S T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17635 590 68894 I104 P R G K N D F I A C F E L I Y
Sea Urchin Strong. purpuratus XP_001197919 631 72734 Q125 S N P I S V K Q L M S P T T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40460 691 80469 F153 N H P I S I K F L K Q P T Q K
Red Bread Mold Neurospora crassa Q96U60 743 84837 F189 N H K L S D N F T K S P T Q K
Conservation
Percent
Protein Identity: 100 99.6 99.2 92.5 N.A. 83.9 44.5 N.A. 75.5 71.3 56.8 44.2 N.A. N.A. N.A. 21.8 28
Protein Similarity: 100 99.6 99.5 97.1 N.A. 91.5 47.9 N.A. 87.9 84.7 77.4 63.8 N.A. N.A. N.A. 44.8 51.2
P-Site Identity: 100 100 100 86.6 N.A. 73.3 0 N.A. 93.3 80 46.6 40 N.A. N.A. N.A. 0 33.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 0 N.A. 93.3 100 73.3 80 N.A. N.A. N.A. 13.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 22.7
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 44.6
P-Site Identity: N.A. N.A. N.A. N.A. 40 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 8 0 0 0 0 8 8 0 43 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 8 0 0 0 0 8 15 0 0 8 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 22 0 15 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 8 8 0 0 79 0 0 15 0 0 0 0 86 % K
% Leu: 0 0 0 15 0 0 0 0 79 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 43 0 0 0 8 0 0 0 0 0 % M
% Asn: 15 8 36 0 8 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 15 0 0 0 0 0 0 0 0 86 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 8 0 65 8 0 0 15 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 22 0 65 0 0 58 0 0 29 0 65 0 0 % S
% Thr: 0 0 0 0 22 0 0 0 8 0 0 0 22 29 0 % T
% Val: 8 0 0 50 0 22 0 0 0 0 0 0 0 43 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _