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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDC80
All Species:
20
Human Site:
S496
Identified Species:
33.85
UniProt:
O14777
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14777
NP_006092.1
642
73913
S496
L
N
A
M
I
T
E
S
K
R
S
V
R
T
L
Chimpanzee
Pan troglodytes
XP_512046
642
73980
S496
L
N
A
M
I
T
E
S
K
R
S
V
R
T
L
Rhesus Macaque
Macaca mulatta
XP_001086615
642
73921
S496
L
N
A
M
I
T
E
S
K
R
S
V
R
T
L
Dog
Lupus familis
XP_537313
642
73907
S496
L
N
T
M
I
T
E
S
R
R
G
V
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F1
642
73943
S496
L
N
T
M
K
T
E
S
K
N
T
V
R
M
L
Rat
Rattus norvegicus
NP_001119742
329
38011
L190
S
K
R
A
V
R
M
L
K
E
E
V
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505423
649
75199
S498
V
N
T
M
V
A
E
S
K
R
T
V
K
M
L
Chicken
Gallus gallus
Q76I89
640
73723
K499
V
N
A
M
V
A
E
K
K
S
S
V
K
T
L
Frog
Xenopus laevis
Q8AWF5
638
74459
K494
L
N
T
L
I
G
E
K
K
N
E
V
K
V
Q
Zebra Danio
Brachydanio rerio
Q6DRJ7
632
73198
K490
V
K
S
N
I
F
D
K
E
N
D
I
K
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17635
590
68894
L451
L
H
Q
R
K
L
E
L
E
T
E
Q
S
R
F
Sea Urchin
Strong. purpuratus
XP_001197919
631
72734
Q492
N
E
E
E
A
H
D
Q
V
K
E
M
T
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40460
691
80469
D549
D
N
I
T
L
E
K
D
I
K
N
L
K
H
D
Red Bread Mold
Neurospora crassa
Q96U60
743
84837
R582
L
R
K
E
V
S
E
R
R
K
V
A
M
D
V
Conservation
Percent
Protein Identity:
100
99.6
99.2
92.5
N.A.
83.9
44.5
N.A.
75.5
71.3
56.8
44.2
N.A.
N.A.
N.A.
21.8
28
Protein Similarity:
100
99.6
99.5
97.1
N.A.
91.5
47.9
N.A.
87.9
84.7
77.4
63.8
N.A.
N.A.
N.A.
44.8
51.2
P-Site Identity:
100
100
100
80
N.A.
66.6
20
N.A.
53.3
60
40
13.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
33.3
N.A.
80
80
53.3
53.3
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
44.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
8
8
15
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
15
8
0
0
8
0
0
8
8
% D
% Glu:
0
8
8
15
0
8
72
0
15
8
29
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
43
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
15
8
0
15
0
8
22
58
22
0
0
36
8
0
% K
% Leu:
58
0
0
8
8
8
0
15
0
0
0
8
0
0
65
% L
% Met:
0
0
0
50
0
0
8
0
0
0
0
8
8
15
0
% M
% Asn:
8
65
0
8
0
0
0
0
0
22
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
8
8
8
8
% Q
% Arg:
0
8
8
8
0
8
0
8
15
36
0
0
36
8
0
% R
% Ser:
8
0
8
0
0
8
0
43
0
8
29
0
8
0
0
% S
% Thr:
0
0
29
8
0
36
0
0
0
8
15
0
8
36
0
% T
% Val:
22
0
0
0
29
0
0
0
8
0
8
65
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _