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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDC80 All Species: 20
Human Site: S496 Identified Species: 33.85
UniProt: O14777 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14777 NP_006092.1 642 73913 S496 L N A M I T E S K R S V R T L
Chimpanzee Pan troglodytes XP_512046 642 73980 S496 L N A M I T E S K R S V R T L
Rhesus Macaque Macaca mulatta XP_001086615 642 73921 S496 L N A M I T E S K R S V R T L
Dog Lupus familis XP_537313 642 73907 S496 L N T M I T E S R R G V R T L
Cat Felis silvestris
Mouse Mus musculus Q9D0F1 642 73943 S496 L N T M K T E S K N T V R M L
Rat Rattus norvegicus NP_001119742 329 38011 L190 S K R A V R M L K E E V Q K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505423 649 75199 S498 V N T M V A E S K R T V K M L
Chicken Gallus gallus Q76I89 640 73723 K499 V N A M V A E K K S S V K T L
Frog Xenopus laevis Q8AWF5 638 74459 K494 L N T L I G E K K N E V K V Q
Zebra Danio Brachydanio rerio Q6DRJ7 632 73198 K490 V K S N I F D K E N D I K Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17635 590 68894 L451 L H Q R K L E L E T E Q S R F
Sea Urchin Strong. purpuratus XP_001197919 631 72734 Q492 N E E E A H D Q V K E M T E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40460 691 80469 D549 D N I T L E K D I K N L K H D
Red Bread Mold Neurospora crassa Q96U60 743 84837 R582 L R K E V S E R R K V A M D V
Conservation
Percent
Protein Identity: 100 99.6 99.2 92.5 N.A. 83.9 44.5 N.A. 75.5 71.3 56.8 44.2 N.A. N.A. N.A. 21.8 28
Protein Similarity: 100 99.6 99.5 97.1 N.A. 91.5 47.9 N.A. 87.9 84.7 77.4 63.8 N.A. N.A. N.A. 44.8 51.2
P-Site Identity: 100 100 100 80 N.A. 66.6 20 N.A. 53.3 60 40 13.3 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 33.3 N.A. 80 80 53.3 53.3 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 22.7
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 44.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 29 8 8 15 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 15 8 0 0 8 0 0 8 8 % D
% Glu: 0 8 8 15 0 8 72 0 15 8 29 0 0 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 8 0 43 0 0 0 8 0 0 8 0 0 0 % I
% Lys: 0 15 8 0 15 0 8 22 58 22 0 0 36 8 0 % K
% Leu: 58 0 0 8 8 8 0 15 0 0 0 8 0 0 65 % L
% Met: 0 0 0 50 0 0 8 0 0 0 0 8 8 15 0 % M
% Asn: 8 65 0 8 0 0 0 0 0 22 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 8 8 8 8 % Q
% Arg: 0 8 8 8 0 8 0 8 15 36 0 0 36 8 0 % R
% Ser: 8 0 8 0 0 8 0 43 0 8 29 0 8 0 0 % S
% Thr: 0 0 29 8 0 36 0 0 0 8 15 0 8 36 0 % T
% Val: 22 0 0 0 29 0 0 0 8 0 8 65 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _