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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDC80 All Species: 20.3
Human Site: S616 Identified Species: 34.36
UniProt: O14777 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14777 NP_006092.1 642 73913 S616 R E Y E E C M S E D L S E N I
Chimpanzee Pan troglodytes XP_512046 642 73980 S616 R E Y E E C M S E D L L E N I
Rhesus Macaque Macaca mulatta XP_001086615 642 73921 S616 R E Y E E C M S E D L S E N I
Dog Lupus familis XP_537313 642 73907 S616 R E Y E E Y V S E D L L E N I
Cat Felis silvestris
Mouse Mus musculus Q9D0F1 642 73943 S616 R E Y E E F M S E D L L E N I
Rat Rattus norvegicus NP_001119742 329 38011 E304 E Y E E C T S E D L L E N I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505423 649 75199 S618 R E F E E F M S E D S L K D L
Chicken Gallus gallus Q76I89 640 73723 E615 S K I D R D Y E E F M S E D L
Frog Xenopus laevis Q8AWF5 638 74459 M613 E R E Y E E F M K E D L L L D
Zebra Danio Brachydanio rerio Q6DRJ7 632 73198 K605 L K R F D K L K D I V R E D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17635 590 68894 V565 R Q I L D L M V V E I A E I E
Sea Urchin Strong. purpuratus XP_001197919 631 72734 H606 K L Q N H V G H L Q Q E A H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40460 691 80469 L664 K I N I Q S S L E N S E N E L
Red Bread Mold Neurospora crassa Q96U60 743 84837 Q708 I K F K M H V Q R S L E E Y E
Conservation
Percent
Protein Identity: 100 99.6 99.2 92.5 N.A. 83.9 44.5 N.A. 75.5 71.3 56.8 44.2 N.A. N.A. N.A. 21.8 28
Protein Similarity: 100 99.6 99.5 97.1 N.A. 91.5 47.9 N.A. 87.9 84.7 77.4 63.8 N.A. N.A. N.A. 44.8 51.2
P-Site Identity: 100 93.3 100 80 N.A. 86.6 13.3 N.A. 53.3 20 6.6 6.6 N.A. N.A. N.A. 20 0
P-Site Similarity: 100 93.3 100 86.6 N.A. 86.6 20 N.A. 80 53.3 20 46.6 N.A. N.A. N.A. 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 22.7
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 44.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 8 22 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 15 8 0 0 15 43 8 0 0 22 8 % D
% Glu: 15 43 15 50 50 8 0 15 58 15 0 29 65 8 22 % E
% Phe: 0 0 15 8 0 15 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 8 0 8 0 0 0 0 0 8 0 % H
% Ile: 8 8 15 8 0 0 0 0 0 8 8 0 0 15 36 % I
% Lys: 15 22 0 8 0 8 0 8 8 0 0 0 8 0 0 % K
% Leu: 8 8 0 8 0 8 8 8 8 8 50 36 8 8 22 % L
% Met: 0 0 0 0 8 0 43 8 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 8 0 0 15 36 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 8 0 0 8 0 8 8 0 0 0 0 % Q
% Arg: 50 8 8 0 8 0 0 0 8 0 0 8 0 0 8 % R
% Ser: 8 0 0 0 0 8 15 43 0 8 15 22 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 15 8 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 36 8 0 8 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _