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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF3C All Species: 20.91
Human Site: S291 Identified Species: 35.38
UniProt: O14782 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14782 NP_002245.4 793 89454 S291 G E R P K E A S K I N L S L S
Chimpanzee Pan troglodytes XP_001149366 793 89463 S291 G E R P K E A S K I N L S L S
Rhesus Macaque Macaca mulatta XP_001084972 793 89433 S291 G E R P K E A S K I N L S L S
Dog Lupus familis XP_849575 779 88618 A291 S A L G N V I A A L A G N R S
Cat Felis silvestris
Mouse Mus musculus O35066 796 89940 S293 G E R P K E A S K I N L S L S
Rat Rattus norvegicus O55165 796 89797 S293 G E R P K E A S K I N L S L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 K537 K E L V E L N K A L A L K E A
Frog Xenopus laevis P28025 1060 119314 P303 V E R T P H I P Y R E S K L T
Zebra Danio Brachydanio rerio NP_001017849 759 86830 V301 V D G K S T H V P Y R D S K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 P295 A E S S P H V P Y R D S K L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 L287 R D S K L T R L L Q D S L G G
Sea Urchin Strong. purpuratus P46871 742 84184 I289 V D G K S S H I P Y R D S K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 S323 L T R L L R D S L G G R T K T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 T354 Q M L A K A K T Q I T S F E N
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.5 N.A. 94.9 95.9 N.A. N.A. 24.5 23.2 58.7 N.A. 43.1 N.A. 34.6 54.9
Protein Similarity: 100 100 99.3 96.7 N.A. 97.2 97.8 N.A. N.A. 38.2 41.5 73.6 N.A. 63.5 N.A. 50.8 72.7
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. N.A. 13.3 20 6.6 N.A. 13.3 N.A. 0 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. N.A. 33.3 26.6 13.3 N.A. 26.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.6 N.A. 26.6
Protein Similarity: N.A. N.A. N.A. 40.5 N.A. 44.7
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 8 36 8 15 0 15 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 22 0 0 0 0 8 0 0 0 15 15 0 0 0 % D
% Glu: 0 58 0 0 8 36 0 0 0 0 8 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 36 0 15 8 0 0 0 0 0 8 8 8 0 8 8 % G
% His: 0 0 0 0 0 15 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 8 0 43 0 0 0 0 0 % I
% Lys: 8 0 0 22 43 0 8 8 36 0 0 0 22 22 0 % K
% Leu: 8 0 22 8 15 8 0 8 15 15 0 43 8 50 15 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 0 0 0 36 0 8 0 8 % N
% Pro: 0 0 0 36 15 0 0 15 15 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % Q
% Arg: 8 0 50 0 0 8 8 0 0 15 15 8 0 8 0 % R
% Ser: 8 0 15 8 15 8 0 43 0 0 0 29 50 0 43 % S
% Thr: 0 8 0 8 0 15 0 8 0 0 8 0 8 0 22 % T
% Val: 22 0 0 8 0 8 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 15 15 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _