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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF3C All Species: 26.67
Human Site: S755 Identified Species: 45.13
UniProt: O14782 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14782 NP_002245.4 793 89454 S755 F L E R P S T S K V R K S R S
Chimpanzee Pan troglodytes XP_001149366 793 89463 S755 F L E R P S T S K V R K S R S
Rhesus Macaque Macaca mulatta XP_001084972 793 89433 S755 F L E R P S T S K V R K S R S
Dog Lupus familis XP_849575 779 88618 S741 F L E R P S T S K V R K S R S
Cat Felis silvestris
Mouse Mus musculus O35066 796 89940 T757 F L E R P S T T K V R K S R S
Rat Rattus norvegicus O55165 796 89797 S757 F L E R P S T S K V R K S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 A1182 F M K K P S T A A S L L V R D
Frog Xenopus laevis P28025 1060 119314 C1008 C I D L S M T C Q E K G G I R
Zebra Danio Brachydanio rerio NP_001017849 759 86830 S715 Y R K R T T A S R V M K A R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 R746 V R N I K S S R G L P S A A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 L659 K L S T S K S L F P S K T P T
Sea Urchin Strong. purpuratus P46871 742 84184 P702 D L D L E V Q P E V F K A K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 N984 L V E E F R E N N S Y E S F A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 T874 G S T R G L G T D A G L G G F
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.5 N.A. 94.9 95.9 N.A. N.A. 24.5 23.2 58.7 N.A. 43.1 N.A. 34.6 54.9
Protein Similarity: 100 100 99.3 96.7 N.A. 97.2 97.8 N.A. N.A. 38.2 41.5 73.6 N.A. 63.5 N.A. 50.8 72.7
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 33.3 6.6 40 N.A. 13.3 N.A. 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 60 33.3 73.3 N.A. 33.3 N.A. 33.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. 23.6 N.A. 26.6
Protein Similarity: N.A. N.A. N.A. 40.5 N.A. 44.7
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 8 8 0 0 22 8 8 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 0 15 0 0 0 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 50 8 8 0 8 0 8 8 0 8 0 0 0 % E
% Phe: 50 0 0 0 8 0 0 0 8 0 8 0 0 8 8 % F
% Gly: 8 0 0 0 8 0 8 0 8 0 8 8 15 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 15 8 8 8 0 0 43 0 8 65 0 8 0 % K
% Leu: 8 58 0 15 0 8 0 8 0 8 8 15 0 0 0 % L
% Met: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 50 0 0 8 0 8 8 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 0 15 0 58 0 8 0 8 8 0 43 0 0 58 8 % R
% Ser: 0 8 8 0 15 58 15 43 0 15 8 8 50 0 58 % S
% Thr: 0 0 8 8 8 8 58 15 0 0 0 0 8 0 15 % T
% Val: 8 8 0 0 0 8 0 0 0 58 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _