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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF3C All Species: 19.7
Human Site: Y349 Identified Species: 33.33
UniProt: O14782 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14782 NP_002245.4 793 89454 Y349 L G P A S H S Y D E S L S T L
Chimpanzee Pan troglodytes XP_001149366 793 89463 Y349 L G P A S H S Y D E S L S T L
Rhesus Macaque Macaca mulatta XP_001084972 793 89433 Y349 L G P A S H S Y D E S L S T L
Dog Lupus familis XP_849575 779 88618 K349 L R F A N R A K N I K N K P R
Cat Felis silvestris
Mouse Mus musculus O35066 796 89940 Y351 L G P A S H S Y D E S L S T L
Rat Rattus norvegicus O55165 796 89797 Y351 L G P A S H S Y D E S L S T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 V595 L S M A K K D V N Q A K L S E
Frog Xenopus laevis P28025 1060 119314 K361 N K P E V N Q K L T K K A L I
Zebra Danio Brachydanio rerio NP_001017849 759 86830 E359 K N K P K I N E D P K D A L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 D353 N Q P I K N E D P Q D A K L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 Y345 K D A L L R E Y Q E E I A R L
Sea Urchin Strong. purpuratus P46871 742 84184 E347 K N K P K I N E D P K D A L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 E381 L I K D L Y G E I E R L K A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 P412 S T P S R L L P E S R A E T P
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.5 N.A. 94.9 95.9 N.A. N.A. 24.5 23.2 58.7 N.A. 43.1 N.A. 34.6 54.9
Protein Similarity: 100 100 99.3 96.7 N.A. 97.2 97.8 N.A. N.A. 38.2 41.5 73.6 N.A. 63.5 N.A. 50.8 72.7
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 13.3 6.6 13.3 N.A. 6.6 N.A. 20 13.3
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. N.A. 40 26.6 26.6 N.A. 20 N.A. 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.6 N.A. 26.6
Protein Similarity: N.A. N.A. N.A. 40.5 N.A. 44.7
P-Site Identity: N.A. N.A. N.A. 20 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 50 0 0 8 0 0 0 8 15 29 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 8 8 50 0 8 15 0 0 0 % D
% Glu: 0 0 0 8 0 0 15 22 8 50 8 0 8 0 15 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 36 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 15 0 0 8 8 0 8 0 0 8 % I
% Lys: 22 8 22 0 29 8 0 15 0 0 29 15 22 0 8 % K
% Leu: 58 0 0 8 15 8 8 0 8 0 0 43 8 29 58 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 15 0 0 8 15 15 0 15 0 0 8 0 0 0 % N
% Pro: 0 0 58 15 0 0 0 8 8 15 0 0 0 8 8 % P
% Gln: 0 8 0 0 0 0 8 0 8 15 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 15 0 0 0 0 15 0 0 8 8 % R
% Ser: 8 8 0 8 36 0 36 0 0 8 36 0 36 8 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 8 0 0 0 43 0 % T
% Val: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 43 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _