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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRP1 All Species: 40.61
Human Site: Y358 Identified Species: 99.26
UniProt: O14786 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14786 NP_001019799.1 923 103134 Y358 K K Y Y V K T Y K I D V S S N
Chimpanzee Pan troglodytes XP_001143690 923 102991 Y358 K K Y Y V K T Y K I D V S S N
Rhesus Macaque Macaca mulatta XP_001087258 923 103002 Y358 K K Y Y V K T Y K I D I S S N
Dog Lupus familis XP_535142 990 109990 Y425 K K Y Y V K T Y R I D I S S N
Cat Felis silvestris
Mouse Mus musculus P97333 923 103002 Y358 K K Y Y V K T Y R V D I S S N
Rat Rattus norvegicus Q9QWJ9 922 103064 Y358 K K Y Y V K T Y R V D I S S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508328 913 102061 Y356 K K Y Y V K T Y R I D I S S N
Chicken Gallus gallus P79795 914 102462 Y356 K E Y Y L K T Y R V D V S S N
Frog Xenopus laevis P28824 928 103398 Y358 K K Y F V K S Y K V D I S S N
Zebra Danio Brachydanio rerio Q8QFX6 923 102474 Y356 K K Y Y V K E Y K V D V S S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.5 89.4 N.A. 92.8 93.1 N.A. 86.3 80.9 71.7 65.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.1 91 N.A. 96 96 N.A. 92 89.1 82.8 78.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 80 80 N.A. 86.6 73.3 73.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 50 0 60 0 0 0 % I
% Lys: 100 90 0 0 0 100 0 0 50 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 10 0 0 0 0 0 100 100 0 % S
% Thr: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 90 0 0 0 0 50 0 40 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 100 90 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _