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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO2
All Species:
23.64
Human Site:
S368
Identified Species:
47.27
UniProt:
O14787
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14787
NP_001129668.1
897
101388
S368
D
D
D
D
D
A
L
S
D
W
N
L
R
K
C
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
S541
D
D
D
D
D
A
L
S
D
W
N
L
R
K
C
Rhesus Macaque
Macaca mulatta
XP_001109480
1095
122474
S576
D
D
D
D
D
A
L
S
D
W
N
L
R
K
C
Dog
Lupus familis
XP_542046
887
100404
S368
D
D
D
D
D
A
L
S
D
W
N
L
R
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG2
887
100438
S368
D
D
D
D
D
A
L
S
D
W
N
L
R
K
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506531
898
101915
L368
D
D
D
D
D
D
T
L
S
D
W
N
L
R
K
Chicken
Gallus gallus
XP_424806
890
101281
I370
E
I
D
D
D
D
A
I
S
D
W
N
L
R
K
Frog
Xenopus laevis
NP_001088608
890
101063
D368
E
D
D
D
D
D
D
D
T
L
S
D
W
N
L
Zebra Danio
Brachydanio rerio
XP_001333833
889
100256
T368
D
E
D
D
D
D
D
T
L
S
D
W
N
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
M368
D
D
E
F
E
D
G
M
D
D
D
S
S
L
S
Honey Bee
Apis mellifera
XP_392373
933
105655
E404
D
E
D
D
T
D
A
E
D
G
C
D
D
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
T395
D
E
D
G
D
V
D
T
Q
W
N
L
R
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
81
98.7
N.A.
98.5
N.A.
N.A.
95.5
85
92.9
92.3
N.A.
72.3
74.9
N.A.
N.A.
Protein Similarity:
100
83.6
81
98.8
N.A.
98.6
N.A.
N.A.
97.7
92.5
96.5
95.6
N.A.
85
84.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
33.3
20
26.6
26.6
N.A.
20
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
40
33.3
40
46.6
N.A.
40
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
42
17
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
50
% C
% Asp:
84
67
92
84
84
50
25
9
59
25
17
17
9
9
0
% D
% Glu:
17
25
9
0
9
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
17
% K
% Leu:
0
0
0
0
0
0
42
9
9
9
0
50
17
17
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
50
17
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
50
17
9
% R
% Ser:
0
0
0
0
0
0
0
42
17
9
9
9
9
0
17
% S
% Thr:
0
0
0
0
9
0
9
17
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
50
17
9
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _