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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO2
All Species:
40.3
Human Site:
S445
Identified Species:
80.61
UniProt:
O14787
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14787
NP_001129668.1
897
101388
S445
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
S618
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Rhesus Macaque
Macaca mulatta
XP_001109480
1095
122474
S653
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Dog
Lupus familis
XP_542046
887
100404
S445
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG2
887
100438
S445
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506531
898
101915
S446
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Chicken
Gallus gallus
XP_424806
890
101281
S448
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Frog
Xenopus laevis
NP_001088608
890
101063
S448
P
H
L
I
Q
C
L
S
D
K
K
A
L
V
R
Zebra Danio
Brachydanio rerio
XP_001333833
889
100256
C447
P
H
L
I
Q
C
L
C
D
K
K
A
L
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
S452
P
Y
L
I
S
C
L
S
D
K
K
A
L
V
R
Honey Bee
Apis mellifera
XP_392373
933
105655
S491
P
Y
L
I
S
C
L
S
D
K
K
A
L
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
N472
P
F
L
V
E
Q
L
N
D
K
W
A
P
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
81
98.7
N.A.
98.5
N.A.
N.A.
95.5
85
92.9
92.3
N.A.
72.3
74.9
N.A.
N.A.
Protein Similarity:
100
83.6
81
98.8
N.A.
98.6
N.A.
N.A.
97.7
92.5
96.5
95.6
N.A.
85
84.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% A
% Cys:
0
0
0
0
0
92
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
92
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
100
92
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
100
0
0
0
0
0
92
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
75
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% R
% Ser:
0
0
0
0
17
0
0
84
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _