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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNPO2 All Species: 45.45
Human Site: S499 Identified Species: 90.91
UniProt: O14787 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14787 NP_001129668.1 897 101388 S499 R V Q E A A C S A F A T L E E
Chimpanzee Pan troglodytes XP_512411 1060 118770 S672 R V Q E A A C S A F A T L E E
Rhesus Macaque Macaca mulatta XP_001109480 1095 122474 S707 R V Q E A A C S A F A T L E E
Dog Lupus familis XP_542046 887 100404 S499 R V Q E A A C S A F A T L E E
Cat Felis silvestris
Mouse Mus musculus Q99LG2 887 100438 S499 R V Q E A A C S A F A T L E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506531 898 101915 S500 R V Q E A A C S A F A T L E E
Chicken Gallus gallus XP_424806 890 101281 S502 R V Q E A A C S A F A T L E E
Frog Xenopus laevis NP_001088608 890 101063 S502 R V Q E A A C S A F A T L E E
Zebra Danio Brachydanio rerio XP_001333833 889 100256 S501 R V Q E A A C S A F A T L E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477368 893 101498 S506 R V Q E A A C S A F A T L E E
Honey Bee Apis mellifera XP_392373 933 105655 S545 R V Q E A A C S A F A T L E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38217 918 103663 V527 Q E A A I S S V A V F I E N A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 81 98.7 N.A. 98.5 N.A. N.A. 95.5 85 92.9 92.3 N.A. 72.3 74.9 N.A. N.A.
Protein Similarity: 100 83.6 81 98.8 N.A. 98.6 N.A. N.A. 97.7 92.5 96.5 95.6 N.A. 85 84.6 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 100 100 N.A. 100 100 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 100 100 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 92 92 0 0 100 0 92 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 92 0 0 0 0 0 0 0 0 9 92 92 % E
% Phe: 0 0 0 0 0 0 0 0 0 92 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 92 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 92 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 9 9 92 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 92 0 0 0 % T
% Val: 0 92 0 0 0 0 0 9 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _