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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO2
All Species:
45.45
Human Site:
Y140
Identified Species:
90.91
UniProt:
O14787
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14787
NP_001129668.1
897
101388
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
Y313
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Rhesus Macaque
Macaca mulatta
XP_001109480
1095
122474
Y348
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Dog
Lupus familis
XP_542046
887
100404
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG2
887
100438
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506531
898
101915
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Chicken
Gallus gallus
XP_424806
890
101281
Y142
S
L
L
D
S
E
D
Y
N
T
C
E
G
A
F
Frog
Xenopus laevis
NP_001088608
890
101063
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
A
F
Zebra Danio
Brachydanio rerio
XP_001333833
889
100256
Y140
N
L
L
N
S
E
D
Y
N
T
C
E
G
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
Y140
E
M
L
D
N
Q
D
Y
N
V
C
E
G
A
F
Honey Bee
Apis mellifera
XP_392373
933
105655
Y176
Q
M
L
D
S
Q
D
Y
N
V
C
E
G
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
S157
Y
Q
L
L
E
L
T
S
N
G
N
E
P
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
81
98.7
N.A.
98.5
N.A.
N.A.
95.5
85
92.9
92.3
N.A.
72.3
74.9
N.A.
N.A.
Protein Similarity:
100
83.6
81
98.8
N.A.
98.6
N.A.
N.A.
97.7
92.5
96.5
95.6
N.A.
85
84.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
86.6
100
93.3
N.A.
60
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
84
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% C
% Asp:
0
0
0
25
0
0
92
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
9
75
0
0
0
0
0
100
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
92
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
92
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
75
100
9
0
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
67
9
0
0
0
100
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
9
9
0
0
0
17
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
84
0
0
9
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
75
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _