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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO2
All Species:
40.61
Human Site:
Y743
Identified Species:
81.21
UniProt:
O14787
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14787
NP_001129668.1
897
101388
Y743
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
Y916
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Rhesus Macaque
Macaca mulatta
XP_001109480
1095
122474
Y951
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Dog
Lupus familis
XP_542046
887
100404
Y743
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG2
887
100438
Y743
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506531
898
101915
Y744
M
G
A
E
M
Q
P
Y
V
Q
M
V
L
N
N
Chicken
Gallus gallus
XP_424806
890
101281
Y746
M
G
I
E
M
Q
P
Y
I
P
M
V
L
H
Q
Frog
Xenopus laevis
NP_001088608
890
101063
Y746
M
G
S
E
M
Q
P
Y
V
P
M
V
L
N
N
Zebra Danio
Brachydanio rerio
XP_001333833
889
100256
Y745
M
G
V
E
M
Q
P
Y
V
A
L
V
L
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
Y749
L
G
E
E
T
K
Q
Y
I
R
L
V
L
S
D
Honey Bee
Apis mellifera
XP_392373
933
105655
Y789
L
G
S
D
T
S
A
Y
I
P
L
I
L
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
L772
L
I
S
E
R
I
D
L
N
T
Y
I
I
D
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
81
98.7
N.A.
98.5
N.A.
N.A.
95.5
85
92.9
92.3
N.A.
72.3
74.9
N.A.
N.A.
Protein Similarity:
100
83.6
81
98.8
N.A.
98.6
N.A.
N.A.
97.7
92.5
96.5
95.6
N.A.
85
84.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
66.6
86.6
66.6
N.A.
33.3
20
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
80
93.3
80
N.A.
80
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
9
% D
% Glu:
0
0
9
92
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
9
9
0
0
9
0
0
25
0
0
17
9
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
0
0
9
0
0
25
0
92
0
0
% L
% Met:
75
0
0
0
75
0
0
0
0
0
67
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
59
59
% N
% Pro:
0
0
0
0
0
0
75
0
0
25
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
75
9
0
0
50
0
0
0
0
17
% Q
% Arg:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
25
0
0
9
0
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
17
0
0
0
0
9
0
0
0
9
0
% T
% Val:
0
0
9
0
0
0
0
0
67
0
0
84
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _