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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HS3ST1
All Species:
34.24
Human Site:
Y188
Identified Species:
83.7
UniProt:
O14792
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14792
NP_005105.1
307
35773
Y188
D
G
R
L
N
V
D
Y
K
A
L
N
R
S
L
Chimpanzee
Pan troglodytes
XP_526526
307
35774
Y188
D
G
R
L
N
V
D
Y
K
A
L
N
R
S
L
Rhesus Macaque
Macaca mulatta
XP_001098224
307
35738
Y188
D
G
R
L
N
V
D
Y
K
A
L
N
R
S
L
Dog
Lupus familis
XP_536238
309
35329
Y190
D
G
R
L
N
V
G
Y
K
A
L
N
R
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O35310
311
35881
Y192
D
G
R
L
N
L
D
Y
K
A
L
N
R
S
L
Rat
Rattus norvegicus
Q9ESG5
311
35792
Y192
D
G
R
L
N
V
D
Y
K
A
L
N
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517620
312
36261
Y193
D
G
Q
L
N
V
D
Y
K
A
I
N
R
S
L
Chicken
Gallus gallus
XP_420786
320
37493
Y196
D
G
E
L
N
V
D
Y
K
A
I
N
R
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396407
369
42423
Q226
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
A
A
R
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799088
345
40139
Y225
N
G
E
I
D
T
S
Y
Q
A
I
K
T
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.3
90.6
N.A.
86.8
86.8
N.A.
81.4
79
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
43.4
Protein Similarity:
100
99.6
98.6
92.2
N.A.
91.3
90.6
N.A.
88.4
89.6
N.A.
N.A.
N.A.
N.A.
57.1
N.A.
62.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
90
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
10
0
70
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
90
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
30
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
80
0
0
10
0
0
0
% K
% Leu:
0
0
0
80
0
10
0
0
0
0
60
0
0
0
80
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
80
0
0
0
0
0
0
80
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
20
10
10
10
10
10
20
10
0
0
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
0
0
0
0
0
90
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _