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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSTN
All Species:
25.15
Human Site:
S221
Identified Species:
55.33
UniProt:
O14793
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14793
NP_005250.1
375
42750
S221
N
W
L
K
Q
P
E
S
N
L
G
I
E
I
K
Chimpanzee
Pan troglodytes
NP_001073388
375
42704
S221
N
W
L
K
Q
P
E
S
N
L
G
I
E
I
K
Rhesus Macaque
Macaca mulatta
XP_001096135
279
31313
F134
W
G
I
E
I
N
A
F
D
P
S
G
T
D
L
Dog
Lupus familis
XP_848358
267
30141
D123
G
I
E
I
N
A
F
D
P
S
G
T
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
O08689
376
42903
S222
N
W
L
K
Q
P
E
S
N
L
G
I
E
I
K
Rat
Rattus norvegicus
O35312
376
42811
S222
N
W
L
K
Q
P
E
S
N
L
G
I
E
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520472
181
20483
I37
D
P
C
S
G
F
W
I
I
R
R
A
R
A
P
Chicken
Gallus gallus
O42220
375
42689
S221
N
W
L
K
Q
P
E
S
N
L
G
I
E
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O42222
374
42057
N221
W
L
K
Q
P
E
T
N
R
G
I
E
I
N
A
Tiger Blowfish
Takifugu rubipres
NP_001027844
376
42679
T222
V
W
L
R
Q
P
E
T
N
W
G
I
E
I
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789990
426
48172
T272
G
W
A
A
E
P
E
T
N
L
G
I
V
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
44.5
45.3
N.A.
96
94.9
N.A.
41.3
92
N.A.
68
61.9
N.A.
N.A.
N.A.
29.1
Protein Similarity:
100
99.7
56
55.4
N.A.
97.8
97.3
N.A.
45
95.4
N.A.
81.5
77.1
N.A.
N.A.
N.A.
48.3
P-Site Identity:
100
100
0
6.6
N.A.
100
100
N.A.
0
100
N.A.
0
66.6
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
20
20
N.A.
100
100
N.A.
6.6
100
N.A.
13.3
80
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
10
0
0
0
0
10
0
10
19
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
10
0
0
0
10
10
0
% D
% Glu:
0
0
10
10
10
10
64
0
0
0
0
10
55
0
10
% E
% Phe:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
0
10
0
0
0
0
10
73
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
10
10
0
0
10
10
0
10
64
10
55
0
% I
% Lys:
0
0
10
46
0
0
0
0
0
0
0
0
0
0
46
% K
% Leu:
0
10
55
0
0
0
0
0
0
55
0
0
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
46
0
0
0
10
10
0
10
64
0
0
0
0
10
10
% N
% Pro:
0
10
0
0
10
64
0
0
10
10
0
0
0
0
10
% P
% Gln:
0
0
0
10
55
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
10
10
10
0
10
0
0
% R
% Ser:
0
0
0
10
0
0
0
46
0
10
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
19
0
0
0
10
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
19
64
0
0
0
0
10
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _