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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSTN All Species: 20
Human Site: S50 Identified Species: 44
UniProt: O14793 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14793 NP_005250.1 375 42750 S50 T W R Q N T K S S R I E A I K
Chimpanzee Pan troglodytes NP_001073388 375 42704 S50 T W R Q N T K S S R I E A I K
Rhesus Macaque Macaca mulatta XP_001096135 279 31313
Dog Lupus familis XP_848358 267 30141
Cat Felis silvestris
Mouse Mus musculus O08689 376 42903 Y51 A W R Q N T R Y S R I E A I K
Rat Rattus norvegicus O35312 376 42811 Y51 A W R Q N T R Y S R I E A I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520472 181 20483
Chicken Gallus gallus O42220 375 42689 S50 T W R Q N T K S S R I E A I K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio O42222 374 42057 L51 E F R Q H S K L M R L H A I K
Tiger Blowfish Takifugu rubipres NP_001027844 376 42679 T52 D V R Q H I K T M R L N A I K
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789990 426 48172 Q98 W L R E Q Q K Q F R I E S I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 44.5 45.3 N.A. 96 94.9 N.A. 41.3 92 N.A. 68 61.9 N.A. N.A. N.A. 29.1
Protein Similarity: 100 99.7 56 55.4 N.A. 97.8 97.3 N.A. 45 95.4 N.A. 81.5 77.1 N.A. N.A. N.A. 48.3
P-Site Identity: 100 100 0 0 N.A. 80 80 N.A. 0 100 N.A. 46.6 46.6 N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 0 0 N.A. 86.6 86.6 N.A. 0 100 N.A. 73.3 66.6 N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 55 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 19 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 55 0 0 73 0 % I
% Lys: 0 0 0 0 0 0 55 0 0 0 0 0 0 0 73 % K
% Leu: 0 10 0 0 0 0 0 10 0 0 19 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 46 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 64 10 10 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 73 0 0 0 19 0 0 73 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 28 46 0 0 0 10 0 0 % S
% Thr: 28 0 0 0 0 46 0 10 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 46 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _