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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC13B
All Species:
5.45
Human Site:
S257
Identified Species:
13.33
UniProt:
O14795
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14795
NP_006368.3
1591
180679
S257
R
R
A
I
S
P
T
S
S
S
R
Y
G
S
S
Chimpanzee
Pan troglodytes
XP_001166329
1593
180791
S257
R
R
A
I
S
P
T
S
S
S
R
Y
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001085980
1606
182441
Y257
S
P
T
S
S
S
R
Y
G
S
S
C
N
V
S
Dog
Lupus familis
XP_544689
2217
251282
V284
I
S
S
S
V
E
V
V
Q
S
E
I
E
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N9
1602
181794
L257
D
S
M
Q
S
Y
D
L
D
Y
P
E
R
R
A
Rat
Rattus norvegicus
Q62769
1622
184044
L257
D
S
M
Q
S
Y
D
L
D
Y
P
E
R
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413798
2097
238862
G595
D
D
S
V
N
W
Y
G
S
S
Q
E
Q
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038630
1742
197943
A263
P
T
G
S
S
R
Y
A
S
S
G
E
L
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726614
2874
320510
R1061
S
P
E
N
V
S
S
R
N
S
N
Y
I
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P27715
2155
245213
A274
S
Y
Y
N
D
E
Y
A
P
S
G
S
S
S
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.7
48.6
N.A.
94.9
92.5
N.A.
N.A.
50.8
N.A.
69.5
N.A.
36.9
N.A.
43.4
N.A.
Protein Similarity:
100
99.6
95.6
59.6
N.A.
96.3
94.6
N.A.
N.A.
62.9
N.A.
79.3
N.A.
46.7
N.A.
56.2
N.A.
P-Site Identity:
100
100
20
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
13.3
N.A.
N.A.
46.6
N.A.
33.3
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
20
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
30
10
0
0
10
0
20
0
20
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
20
0
0
0
0
10
40
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
10
0
20
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
20
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
20
0
0
0
0
10
0
10
% L
% Met:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
10
0
0
0
10
0
10
0
10
10
0
% N
% Pro:
10
20
0
0
0
20
0
0
10
0
20
0
0
10
0
% P
% Gln:
0
0
0
20
0
0
0
0
10
0
10
0
10
10
10
% Q
% Arg:
20
20
0
0
0
10
10
10
0
0
20
0
20
20
10
% R
% Ser:
30
30
20
30
60
20
10
20
40
80
10
10
10
40
30
% S
% Thr:
0
10
10
0
0
0
20
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
20
0
10
10
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
20
30
10
0
20
0
30
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _