KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH2D1B
All Species:
12.63
Human Site:
Y127
Identified Species:
55.59
UniProt:
O14796
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14796
NP_444512.2
132
15297
Y127
F
V
N
S
N
S
D
Y
V
D
V
L
P
_
_
Chimpanzee
Pan troglodytes
XP_513952
281
31278
Y127
F
V
K
Q
Y
S
D
Y
V
D
V
L
C
S
A
Rhesus Macaque
Macaca mulatta
XP_001118174
132
15284
Y127
F
M
N
S
N
S
D
Y
V
D
V
L
P
_
_
Dog
Lupus familis
XP_851826
144
16758
S137
I
Y
E
N
N
S
N
S
D
Y
V
E
V
L
P
Cat
Felis silvestris
Mouse
Mus musculus
O35324
132
15240
Y127
Y
E
N
T
D
E
E
Y
V
D
V
L
P
_
_
Rat
Rattus norvegicus
B2RZ59
126
13973
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
96.9
65.9
N.A.
65.1
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
46.6
99.2
83.3
N.A.
81.8
62.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
92.3
20
N.A.
53.8
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
33.3
N.A.
84.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
0
0
17
0
50
0
17
67
0
0
0
0
0
% D
% Glu:
0
17
17
0
0
17
17
0
0
0
0
17
0
0
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
67
0
17
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
17
50
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
17
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
67
0
17
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
34
0
0
0
0
0
0
67
0
84
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
17
0
0
17
0
0
67
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
50
% _