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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3A All Species: 18.18
Human Site: S659 Identified Species: 40
UniProt: O14802 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14802 NP_008986.2 1390 155641 S659 K G T L G S G S K N N I F Y I
Chimpanzee Pan troglodytes XP_507865 1349 150791 S618 K G T L G S G S K N N I F Y I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536399 1390 155706 S659 K G T L G S G S K N N I F Y I
Cat Felis silvestris
Mouse Mus musculus P08775 1970 217158 A649 K K S L G T S A G S L V H I S
Rat Rattus norvegicus O54889 1716 194174 A765 K A H Y G S S A Y G L V H C C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514706 1382 154562 S651 K G T L G S G S K N N I F Y I
Chicken Gallus gallus Q5ZL98 1390 155685 S659 K G T L G S G S K N N I F Y I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04052 1887 209150 A641 K K S L G T S A G S L L H I C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P16356 1852 203961 A639 S K T V G K S A G N L L H V V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P18616 1840 204671 N646 K K T L G T S N G S L V H V I
Baker's Yeast Sacchar. cerevisiae P04051 1460 162283 K673 K S V L G D G K K H S V F Y T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 N.A. 98.8 N.A. 26 26.8 N.A. 95.9 96.2 N.A. N.A. N.A. 27.4 N.A. 27.8 N.A.
Protein Similarity: 100 96.6 N.A. 99.5 N.A. 40.8 43.9 N.A. 98.1 98.5 N.A. N.A. N.A. 43.1 N.A. 43.9 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 20 20 N.A. 100 100 N.A. N.A. N.A. 20 N.A. 20 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 53.3 33.3 N.A. 100 100 N.A. N.A. N.A. 53.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.7 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 68.2 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 37 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 19 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % F
% Gly: 0 46 0 0 100 0 55 0 37 10 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 10 0 0 46 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 46 0 19 55 % I
% Lys: 91 37 0 0 0 10 0 10 55 0 0 0 0 0 0 % K
% Leu: 0 0 0 82 0 0 0 0 0 0 46 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 55 46 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 19 0 0 55 46 46 0 28 10 0 0 0 10 % S
% Thr: 0 0 64 0 0 28 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 10 10 0 0 0 0 0 0 0 37 0 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 0 0 55 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _