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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3A All Species: 19.39
Human Site: T1148 Identified Species: 42.67
UniProt: O14802 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14802 NP_008986.2 1390 155641 T1148 R L E V N A E T V R Y S I C T
Chimpanzee Pan troglodytes XP_507865 1349 150791 T1107 R L E V N A E T V R Y S I C T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536399 1390 155706 T1148 R L E V N A E T V R Y S I C M
Cat Felis silvestris
Mouse Mus musculus P08775 1970 217158 D1223 L D R K H M T D R K L T M E Q
Rat Rattus norvegicus O54889 1716 194174 S1369 K K K N S K A S A F R S V N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514706 1382 154562 T1140 R L E V N A E T V R Y S I C M
Chicken Gallus gallus Q5ZL98 1390 155685 T1148 R L E V N A E T V R Y S I C I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04052 1887 209150 Q1222 D K K L T M E Q I A E K I N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P16356 1852 203961 R1210 R I E L D R K R M V D K K L T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P18616 1840 204671 V1202 Y E M P D E D V S P D K I S P
Baker's Yeast Sacchar. cerevisiae P04051 1460 162283 D1204 Q L E L T I E D I A V A I T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 N.A. 98.8 N.A. 26 26.8 N.A. 95.9 96.2 N.A. N.A. N.A. 27.4 N.A. 27.8 N.A.
Protein Similarity: 100 96.6 N.A. 99.5 N.A. 40.8 43.9 N.A. 98.1 98.5 N.A. N.A. N.A. 43.1 N.A. 43.9 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 0 13.3 N.A. 93.3 93.3 N.A. N.A. N.A. 13.3 N.A. 20 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 26.6 46.6 N.A. 93.3 93.3 N.A. N.A. N.A. 33.3 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.7 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 68.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 46 10 0 10 19 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % C
% Asp: 10 10 0 0 19 0 10 19 0 0 19 0 0 0 0 % D
% Glu: 0 10 64 0 0 10 64 0 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 19 0 0 0 73 0 10 % I
% Lys: 10 19 19 10 0 10 10 0 0 10 0 28 10 0 0 % K
% Leu: 10 55 0 28 0 0 0 0 0 0 10 0 0 10 0 % L
% Met: 0 0 10 0 0 19 0 0 10 0 0 0 10 0 19 % M
% Asn: 0 0 0 10 46 0 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 10 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % Q
% Arg: 55 0 10 0 0 10 0 10 10 46 10 0 0 0 10 % R
% Ser: 0 0 0 0 10 0 0 10 10 0 0 55 0 10 0 % S
% Thr: 0 0 0 0 19 0 10 46 0 0 0 10 0 10 37 % T
% Val: 0 0 0 46 0 0 0 10 46 10 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _