KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRAS
All Species:
22.73
Human Site:
S75
Identified Species:
38.46
UniProt:
O14807
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14807
NP_001078518.1
208
23846
S75
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
Chimpanzee
Pan troglodytes
XP_001171965
204
23353
G76
T
A
G
Q
E
E
F
G
A
M
R
E
Q
Y
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08989
208
23883
S75
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
Rat
Rattus norvegicus
P97538
208
23869
S75
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507773
243
27878
S110
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
Chicken
Gallus gallus
NP_989820
208
23771
S75
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
Frog
Xenopus laevis
Q7ZXH7
184
20815
M72
T
A
M
R
D
L
Y
M
K
N
G
Q
G
F
A
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
M72
T
A
M
R
D
L
Y
M
K
N
G
Q
G
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04388
192
22217
R75
A
M
R
E
Q
Y
M
R
S
G
E
G
F
L
L
Honey Bee
Apis mellifera
XP_393895
198
22919
A75
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
M
R
Nematode Worm
Caenorhab. elegans
NP_497972
211
24021
S79
T
A
G
Q
E
E
F
S
A
M
R
E
Q
Y
I
Sea Urchin
Strong. purpuratus
XP_784862
177
19938
D65
D
G
D
W
C
I
L
D
V
L
D
T
A
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P01119
309
34328
V110
Y
Y
Q
Q
I
Q
R
V
K
D
S
D
Y
I
P
Red Bread Mold
Neurospora crassa
P22126
213
24008
Q75
E
Y
S
A
M
R
E
Q
Y
M
R
T
G
E
G
Conservation
Percent
Protein Identity:
100
55.2
N.A.
N.A.
N.A.
96.6
97.1
N.A.
62.9
97.5
46.1
45.6
N.A.
50
68.7
54
62.9
Protein Similarity:
100
70.1
N.A.
N.A.
N.A.
99.5
99.5
N.A.
69.5
99
63.4
63.4
N.A.
69.7
82.6
71
74
P-Site Identity:
100
93.3
N.A.
N.A.
N.A.
100
100
N.A.
100
100
13.3
13.3
N.A.
0
6.6
93.3
0
P-Site Similarity:
100
93.3
N.A.
N.A.
N.A.
100
100
N.A.
100
100
46.6
46.6
N.A.
26.6
26.6
100
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.6
49.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
66.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
65
0
8
0
0
0
8
50
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
15
0
0
8
0
8
8
8
0
0
0
% D
% Glu:
8
0
0
15
58
50
8
0
0
0
15
50
0
8
0
% E
% Phe:
0
0
0
0
0
8
50
0
0
0
0
0
8
15
0
% F
% Gly:
0
15
50
0
0
0
0
8
0
8
15
8
22
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
8
0
0
8
0
0
0
8
8
% L
% Met:
0
8
15
0
8
0
8
15
8
58
0
0
0
8
43
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
15
58
8
8
0
8
0
0
0
22
50
0
8
% Q
% Arg:
0
0
8
15
0
8
8
8
0
8
58
0
0
0
8
% R
% Ser:
0
0
8
0
0
0
8
43
8
0
8
0
0
0
0
% S
% Thr:
65
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
15
0
0
0
8
15
0
8
0
0
0
15
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _