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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRAS
All Species:
19.7
Human Site:
T190
Identified Species:
33.33
UniProt:
O14807
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14807
NP_001078518.1
208
23846
T190
S
Q
K
K
K
K
K
T
K
W
R
G
D
R
A
Chimpanzee
Pan troglodytes
XP_001171965
204
23353
S186
Q
E
Q
E
C
P
P
S
P
E
P
T
R
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08989
208
23883
T190
N
Q
K
K
K
K
K
T
K
W
R
G
D
R
A
Rat
Rattus norvegicus
P97538
208
23869
T190
N
Q
K
K
K
K
K
T
K
W
R
G
D
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507773
243
27878
T225
S
Q
K
K
K
K
K
T
K
W
R
G
D
R
A
Chicken
Gallus gallus
NP_989820
208
23771
T190
S
Q
K
K
K
K
K
T
K
W
R
G
D
R
A
Frog
Xenopus laevis
Q7ZXH7
184
20815
R167
D
L
V
R
Q
I
N
R
K
T
P
V
P
G
K
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
R167
D
L
V
R
Q
I
N
R
K
T
P
V
T
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04388
192
22217
R174
R
K
F
Q
I
A
E
R
P
F
I
E
Q
D
Y
Honey Bee
Apis mellifera
XP_393895
198
22919
A180
I
I
R
N
Q
P
P
A
E
L
E
K
N
R
R
Nematode Worm
Caenorhab. elegans
NP_497972
211
24021
M193
E
G
D
H
E
A
S
M
A
S
V
P
R
T
K
Sea Urchin
Strong. purpuratus
XP_784862
177
19938
K160
P
Y
I
E
T
S
A
K
D
P
P
K
N
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P01119
309
34328
Q290
S
K
Q
S
A
E
P
Q
K
N
S
S
A
N
A
Red Bread Mold
Neurospora crassa
P22126
213
24008
D173
V
R
E
I
R
K
E
D
K
K
L
G
E
K
V
Conservation
Percent
Protein Identity:
100
55.2
N.A.
N.A.
N.A.
96.6
97.1
N.A.
62.9
97.5
46.1
45.6
N.A.
50
68.7
54
62.9
Protein Similarity:
100
70.1
N.A.
N.A.
N.A.
99.5
99.5
N.A.
69.5
99
63.4
63.4
N.A.
69.7
82.6
71
74
P-Site Identity:
100
0
N.A.
N.A.
N.A.
93.3
93.3
N.A.
100
100
6.6
6.6
N.A.
0
6.6
0
0
P-Site Similarity:
100
33.3
N.A.
N.A.
N.A.
100
100
N.A.
100
100
20
20
N.A.
26.6
33.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.6
49.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
66.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
8
8
8
0
0
0
8
0
43
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
0
0
0
0
8
8
0
0
0
36
8
8
% D
% Glu:
8
8
8
15
8
8
15
0
8
8
8
8
8
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
43
0
15
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
8
15
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
15
36
36
36
43
36
8
65
8
0
15
0
15
22
% K
% Leu:
0
15
0
0
0
0
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
8
0
0
15
0
0
8
0
0
15
8
0
% N
% Pro:
8
0
0
0
0
15
22
0
15
8
29
8
8
0
0
% P
% Gln:
8
36
15
8
22
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
8
8
8
15
8
0
0
22
0
0
36
0
15
43
8
% R
% Ser:
29
0
0
8
0
8
8
8
0
8
8
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
36
0
15
0
8
8
8
0
% T
% Val:
8
0
15
0
0
0
0
0
0
0
8
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _