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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRAS
All Species:
22.12
Human Site:
T45
Identified Species:
37.44
UniProt:
O14807
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14807
NP_001078518.1
208
23846
T45
F
V
P
D
Y
D
P
T
I
E
D
S
Y
L
K
Chimpanzee
Pan troglodytes
XP_001171965
204
23353
T46
F
V
T
D
Y
D
P
T
I
E
D
S
Y
T
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08989
208
23883
T45
F
V
P
D
Y
D
P
T
I
E
D
S
Y
L
K
Rat
Rattus norvegicus
P97538
208
23869
T45
F
V
P
D
Y
D
P
T
I
E
D
S
Y
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507773
243
27878
L80
G
S
G
P
A
T
V
L
A
V
S
L
E
E
R
Chicken
Gallus gallus
NP_989820
208
23771
T45
F
V
P
D
Y
D
P
T
I
E
D
S
Y
L
K
Frog
Xenopus laevis
Q7ZXH7
184
20815
K42
T
I
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
K42
T
I
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04388
192
22217
Q45
I
E
D
S
Y
T
K
Q
C
N
I
D
D
V
P
Honey Bee
Apis mellifera
XP_393895
198
22919
I45
V
T
D
Y
D
P
T
I
E
D
S
Y
I
Q
H
Nematode Worm
Caenorhab. elegans
NP_497972
211
24021
T49
F
V
D
Y
Y
D
P
T
I
E
D
Q
Y
I
Q
Sea Urchin
Strong. purpuratus
XP_784862
177
19938
F35
S
A
I
T
I
Q
F
F
Q
K
L
F
V
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P01119
309
34328
R80
A
M
R
E
Q
Y
M
R
T
G
E
G
F
L
L
Red Bread Mold
Neurospora crassa
P22126
213
24008
Y45
D
P
T
I
E
D
S
Y
R
K
Q
C
T
I
D
Conservation
Percent
Protein Identity:
100
55.2
N.A.
N.A.
N.A.
96.6
97.1
N.A.
62.9
97.5
46.1
45.6
N.A.
50
68.7
54
62.9
Protein Similarity:
100
70.1
N.A.
N.A.
N.A.
99.5
99.5
N.A.
69.5
99
63.4
63.4
N.A.
69.7
82.6
71
74
P-Site Identity:
100
86.6
N.A.
N.A.
N.A.
100
100
N.A.
0
100
6.6
6.6
N.A.
6.6
0
66.6
0
P-Site Similarity:
100
86.6
N.A.
N.A.
N.A.
100
100
N.A.
6.6
100
26.6
26.6
N.A.
13.3
6.6
80
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.6
49.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
66.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
8
0
22
50
8
50
0
0
0
8
43
8
22
0
15
% D
% Glu:
0
8
15
8
8
0
0
0
8
43
22
0
8
8
0
% E
% Phe:
43
0
0
0
0
0
8
8
0
0
0
8
8
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
8
0
8
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
15
8
8
8
0
0
8
43
0
8
0
8
15
0
% I
% Lys:
0
0
0
0
0
0
8
15
0
15
0
0
0
0
36
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
8
0
36
8
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
29
8
0
8
43
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
8
8
0
8
22
0
8
8
0
8
22
% Q
% Arg:
0
0
8
0
0
0
15
8
8
0
0
0
0
0
8
% R
% Ser:
8
8
0
8
15
0
8
0
0
0
15
36
0
0
0
% S
% Thr:
15
8
15
8
0
15
8
43
8
0
0
0
8
8
0
% T
% Val:
8
43
0
0
0
0
8
0
0
22
0
15
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
50
22
0
8
0
0
0
8
43
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _