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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN4
All Species:
15.45
Human Site:
T135
Identified Species:
37.78
UniProt:
O14817
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14817
NP_001020405.1
238
26118
T135
T
Q
G
N
V
G
L
T
N
A
W
S
I
I
Q
Chimpanzee
Pan troglodytes
XP_508209
238
26127
T135
T
Q
G
N
V
G
L
T
N
A
W
S
I
I
Q
Rhesus Macaque
Macaca mulatta
XP_001117993
394
43364
K135
T
E
N
N
V
G
L
K
N
A
W
N
I
I
Q
Dog
Lupus familis
XP_854185
257
28132
T154
T
P
G
N
V
G
L
T
N
A
W
S
I
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCK3
238
26035
T135
T
Q
G
N
V
G
L
T
N
A
W
S
I
I
Q
Rat
Rattus norvegicus
P24485
219
24149
A115
K
K
I
N
T
L
V
A
E
G
L
N
D
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512431
219
24622
N115
K
K
V
D
D
Y
V
N
T
E
L
K
D
S
F
Chicken
Gallus gallus
Q5ZIF5
305
35238
T147
L
P
R
Y
Q
W
L
T
H
A
W
N
F
F
Q
Frog
Xenopus laevis
Q6DCQ3
239
26764
K135
S
E
N
N
V
G
L
K
N
A
W
N
I
I
Q
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
R135
T
D
N
N
V
G
L
R
N
A
W
N
I
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
36.7
81.7
N.A.
93.6
37.3
N.A.
43.2
25.5
55.6
56
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
46.7
85.5
N.A.
97.4
58.4
N.A.
61.7
41.3
73.2
71.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
93.3
N.A.
100
6.6
N.A.
0
33.3
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
93.3
N.A.
100
26.6
N.A.
20
46.6
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
80
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
0
0
0
0
0
0
0
20
0
0
% D
% Glu:
0
20
0
0
0
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% F
% Gly:
0
0
40
0
0
70
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
70
70
10
% I
% Lys:
20
20
0
0
0
0
0
20
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
0
0
10
80
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
30
80
0
0
0
10
70
0
0
50
0
0
0
% N
% Pro:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
30
0
0
10
0
0
0
0
0
0
0
0
0
80
% Q
% Arg:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
40
0
20
0
% S
% Thr:
60
0
0
0
10
0
0
50
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
70
0
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
80
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _