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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPEF2 All Species: 18.18
Human Site: S113 Identified Species: 36.36
UniProt: O14830 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14830 NP_006230.2 753 86518 S113 E S I E V P D S Y T G P R L S
Chimpanzee Pan troglodytes XP_526584 753 86517 S113 E S I E V P D S Y T G P R L S
Rhesus Macaque Macaca mulatta XP_001100042 753 86580 S113 E S I E V P D S Y T G P R L S
Dog Lupus familis XP_544934 970 109306 P225 E R C P S P P P S P G G P S L
Cat Felis silvestris
Mouse Mus musculus O35385 757 86627 S113 E S I E V P D S Y T G P R L S
Rat Rattus norvegicus Q3SWT6 640 73948 I23 V V R A A L I I Q N W Y R R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510316 925 101565 S113 E S I E V P D S Y T G P R L S
Chicken Gallus gallus XP_420595 713 82896 F96 M F I S G E S F K E A E L E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108202 718 82122 Q101 P L T E E V R Q L K Y E Q I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40421 661 75493 D44 L E Y A S E Q D Q A E L Y K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780182 694 79630 D77 M Q T V S E D D S K S K Y I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9UW86 308 35549
Conservation
Percent
Protein Identity: 100 99.1 95.4 55 N.A. 82.6 43 N.A. 26 66.2 N.A. 52.5 N.A. 29.3 N.A. N.A. 36.2
Protein Similarity: 100 99.8 97.7 62.4 N.A. 90.8 61.6 N.A. 37.7 77.5 N.A. 66.2 N.A. 46.3 N.A. N.A. 52.9
P-Site Identity: 100 100 100 20 N.A. 100 6.6 N.A. 100 6.6 N.A. 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 100 6.6 N.A. 100 6.6 N.A. 20 N.A. 0 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.1
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 29.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 9 0 0 0 0 9 9 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 17 0 0 0 0 0 0 0 % D
% Glu: 50 9 0 50 9 25 0 0 0 9 9 17 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 50 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 50 0 0 0 9 9 0 0 0 0 0 17 9 % I
% Lys: 0 0 0 0 0 0 0 0 9 17 0 9 0 9 9 % K
% Leu: 9 9 0 0 0 9 0 0 9 0 0 9 9 42 9 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 0 0 9 0 50 9 9 0 9 0 42 9 0 0 % P
% Gln: 0 9 0 0 0 0 9 9 17 0 0 0 9 0 0 % Q
% Arg: 0 9 9 0 0 0 9 0 0 0 0 0 50 9 0 % R
% Ser: 0 42 0 9 25 0 9 42 17 0 9 0 0 9 42 % S
% Thr: 0 0 17 0 0 0 0 0 0 42 0 0 0 0 0 % T
% Val: 9 9 0 9 42 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 42 0 9 9 17 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _