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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPEF2 All Species: 19.09
Human Site: S618 Identified Species: 38.18
UniProt: O14830 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14830 NP_006230.2 753 86518 S618 R P Q L V N S S A D N M L E Y
Chimpanzee Pan troglodytes XP_526584 753 86517 S618 R P Q L V N S S A D N M L E Y
Rhesus Macaque Macaca mulatta XP_001100042 753 86580 S618 R S Q L V N S S A D N M L E Y
Dog Lupus familis XP_544934 970 109306 S824 K P Q L V N S S T D N T L E Y
Cat Felis silvestris
Mouse Mus musculus O35385 757 86627 S622 R P Q L V N S S A D N V L E Y
Rat Rattus norvegicus Q3SWT6 640 73948 L515 L N L P W R S L S S H L V S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510316 925 101565 V735 R L L S G S S V E G T A P T G
Chicken Gallus gallus XP_420595 713 82896 L588 A V E S V L R L G L P W R M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108202 718 82122 T593 R L D L P W R T L R P R L A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40421 661 75493 N536 A S L V A I F N I I D A D N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780182 694 79630 Y569 N E N G L I E Y D S C L E M E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9UW86 308 35549 M183 L S P D L N S M E Q I R R V M
Conservation
Percent
Protein Identity: 100 99.1 95.4 55 N.A. 82.6 43 N.A. 26 66.2 N.A. 52.5 N.A. 29.3 N.A. N.A. 36.2
Protein Similarity: 100 99.8 97.7 62.4 N.A. 90.8 61.6 N.A. 37.7 77.5 N.A. 66.2 N.A. 46.3 N.A. N.A. 52.9
P-Site Identity: 100 100 93.3 80 N.A. 93.3 6.6 N.A. 13.3 6.6 N.A. 20 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 100 33.3 N.A. 20 13.3 N.A. 26.6 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.1
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 29.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 9 0 0 0 34 0 0 17 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 9 9 0 0 0 0 9 42 9 0 9 0 0 % D
% Glu: 0 9 9 0 0 0 9 0 17 0 0 0 9 42 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 0 0 9 9 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 0 9 9 9 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 17 25 50 17 9 0 17 9 9 0 17 50 0 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 25 0 17 9 % M
% Asn: 9 9 9 0 0 50 0 9 0 0 42 0 0 9 0 % N
% Pro: 0 34 9 9 9 0 0 0 0 0 17 0 9 0 0 % P
% Gln: 0 0 42 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 9 17 0 0 9 0 17 17 0 9 % R
% Ser: 0 25 0 17 0 9 67 42 9 17 0 0 0 9 9 % S
% Thr: 0 0 0 0 0 0 0 9 9 0 9 9 0 9 9 % T
% Val: 0 9 0 9 50 0 0 9 0 0 0 9 9 9 0 % V
% Trp: 0 0 0 0 9 9 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _