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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
11.36
Human Site:
S749
Identified Species:
22.73
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
S749
A
K
D
S
G
C
S
S
P
G
A
H
_
_
_
Chimpanzee
Pan troglodytes
XP_526584
753
86517
S749
A
K
D
S
G
C
S
S
P
G
A
H
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
S749
A
K
D
S
G
C
N
S
P
G
A
C
_
_
_
Dog
Lupus familis
XP_544934
970
109306
Q955
T
D
N
Q
A
A
N
Q
A
N
T
K
N
S
V
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
S753
T
A
E
S
G
H
S
S
P
G
P
C
_
_
_
Rat
Rattus norvegicus
Q3SWT6
640
73948
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
P861
A
P
A
D
G
P
V
P
L
A
G
P
R
P
R
Chicken
Gallus gallus
XP_420595
713
82896
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
100
83.3
0
N.A.
50
0
N.A.
13.3
0
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
91.6
13.3
N.A.
58.3
0
N.A.
13.3
0
N.A.
0
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
0
9
9
0
0
9
9
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
17
0
0
0
% C
% Asp:
0
9
25
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
42
0
0
0
0
34
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
17
0
0
9
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
9
0
9
34
0
9
9
0
9
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
0
34
0
0
25
34
0
0
0
0
0
9
0
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
34
34
34
% _