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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
16.36
Human Site:
T434
Identified Species:
32.73
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
T434
A
G
E
L
R
K
P
T
Q
E
E
W
R
Q
V
Chimpanzee
Pan troglodytes
XP_526584
753
86517
T434
A
G
E
L
R
K
P
T
Q
E
E
W
R
Q
V
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
T434
A
G
E
L
Q
K
P
T
Q
E
E
W
R
Q
V
Dog
Lupus familis
XP_544934
970
109306
T635
S
P
E
P
L
Q
P
T
Q
E
A
W
K
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
T438
G
G
G
V
L
E
P
T
P
E
E
W
K
Q
V
Rat
Rattus norvegicus
Q3SWT6
640
73948
A334
A
G
P
S
E
Q
S
A
S
E
Q
L
T
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
I522
L
E
I
T
D
D
T
I
S
S
L
A
R
S
I
Chicken
Gallus gallus
XP_420595
713
82896
V407
E
L
T
C
S
S
L
V
S
L
T
D
L
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
P412
D
S
F
V
S
L
E
P
P
E
L
P
R
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
Y355
L
Q
R
H
R
L
S
Y
V
I
R
S
H
E
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
K388
L
I
R
S
H
E
C
K
P
D
G
Y
E
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
100
93.3
53.3
N.A.
53.3
20
N.A.
6.6
0
N.A.
13.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
46.6
N.A.
13.3
0
N.A.
26.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
0
9
9
0
0
0
9
0
9
0
9
0
% D
% Glu:
9
9
34
0
9
17
9
0
0
59
34
0
9
17
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
42
9
0
0
0
0
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
9
0
0
0
0
9
0
9
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
25
0
9
0
0
0
0
17
9
0
% K
% Leu:
25
9
0
25
17
17
9
0
0
9
17
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
9
0
0
42
9
25
0
0
9
0
0
0
% P
% Gln:
0
9
0
0
9
17
0
0
34
0
9
0
0
42
0
% Q
% Arg:
0
0
17
0
25
0
0
0
0
0
9
0
42
0
0
% R
% Ser:
9
9
0
17
17
9
17
0
25
9
0
9
0
9
0
% S
% Thr:
0
0
9
9
0
0
9
42
0
0
9
0
9
0
9
% T
% Val:
0
0
0
17
0
0
0
9
9
0
0
0
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _