KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
13.03
Human Site:
Y105
Identified Species:
26.06
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
Y105
E
M
K
K
C
S
D
Y
E
S
I
E
V
P
D
Chimpanzee
Pan troglodytes
XP_526584
753
86517
Y105
E
M
E
K
C
S
D
Y
E
S
I
E
V
P
D
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
Y105
E
M
E
K
C
S
D
Y
E
S
I
E
V
P
D
Dog
Lupus familis
XP_544934
970
109306
Q217
L
S
L
E
T
L
F
Q
E
R
C
P
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
F105
E
T
E
E
G
G
D
F
E
S
I
E
V
P
D
Rat
Rattus norvegicus
Q3SWT6
640
73948
K15
K
K
G
K
K
S
E
K
V
V
R
A
A
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
Y105
K
I
K
E
C
C
L
Y
E
S
I
E
V
P
D
Chicken
Gallus gallus
XP_420595
713
82896
R88
K
E
R
D
F
I
S
R
M
F
I
S
G
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
D93
H
L
L
D
S
V
V
D
P
L
T
E
E
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
N36
C
N
W
Q
I
F
Q
N
L
E
Y
A
S
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
M69
L
Y
N
F
F
N
S
M
M
Q
T
V
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
93.3
93.3
13.3
N.A.
60
13.3
N.A.
66.6
6.6
N.A.
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
80
26.6
N.A.
86.6
20
N.A.
13.3
N.A.
6.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% A
% Cys:
9
0
0
0
34
9
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
34
9
0
0
0
0
0
0
50
% D
% Glu:
34
9
25
25
0
0
9
0
50
9
0
50
9
25
0
% E
% Phe:
0
0
0
9
17
9
9
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
9
0
0
0
0
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
9
0
0
0
0
50
0
0
0
9
% I
% Lys:
25
9
17
34
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
17
9
17
0
0
9
9
0
9
9
0
0
0
9
0
% L
% Met:
0
25
0
0
0
0
0
9
17
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
9
0
50
9
% P
% Gln:
0
0
0
9
0
0
9
9
0
9
0
0
0
0
9
% Q
% Arg:
0
0
9
0
0
0
0
9
0
9
9
0
0
0
9
% R
% Ser:
0
9
0
0
9
34
17
0
0
42
0
9
25
0
9
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
9
9
0
9
42
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
34
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _