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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
19.7
Human Site:
Y625
Identified Species:
39.39
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
Y625
S
A
D
N
M
L
E
Y
K
S
W
L
K
N
L
Chimpanzee
Pan troglodytes
XP_526584
753
86517
Y625
S
A
D
N
M
L
E
Y
K
S
W
L
K
N
L
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
Y625
S
A
D
N
M
L
E
Y
K
S
W
L
K
N
L
Dog
Lupus familis
XP_544934
970
109306
Y831
S
T
D
N
T
L
E
Y
K
S
W
L
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
Y629
S
A
D
N
V
L
E
Y
R
S
W
L
D
S
L
Rat
Rattus norvegicus
Q3SWT6
640
73948
T522
L
S
S
H
L
V
S
T
D
S
S
G
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
G742
V
E
G
T
A
P
T
G
S
T
A
P
T
P
S
Chicken
Gallus gallus
XP_420595
713
82896
L595
L
G
L
P
W
R
M
L
R
P
Q
L
V
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
R600
T
L
R
P
R
L
A
R
L
G
T
D
G
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
S543
N
I
I
D
A
D
N
S
G
E
I
T
L
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
E576
Y
D
S
C
L
E
M
E
L
Q
Y
S
G
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
M190
M
E
Q
I
R
R
V
M
R
P
T
D
I
P
D
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
100
100
73.3
N.A.
73.3
6.6
N.A.
0
6.6
N.A.
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
33.3
N.A.
6.6
13.3
N.A.
26.6
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
17
0
9
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
42
9
0
9
0
0
9
0
0
17
9
17
17
% D
% Glu:
0
17
0
0
0
9
42
9
0
9
0
0
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
9
9
9
0
9
17
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
9
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
34
0
0
0
25
0
9
% K
% Leu:
17
9
9
0
17
50
0
9
17
0
0
50
9
0
42
% L
% Met:
9
0
0
0
25
0
17
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
42
0
0
9
0
0
0
0
0
0
34
0
% N
% Pro:
0
0
0
17
0
9
0
0
0
17
0
9
0
17
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
9
0
17
17
0
9
25
0
0
0
0
9
0
% R
% Ser:
42
9
17
0
0
0
9
9
9
50
9
9
9
9
17
% S
% Thr:
9
9
0
9
9
0
9
9
0
9
17
9
9
0
0
% T
% Val:
9
0
0
0
9
9
9
0
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
42
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
42
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _