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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYH All Species: 20.3
Human Site: S109 Identified Species: 44.67
UniProt: O14832 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14832 NP_006205.1 338 38538 S109 R D V T I S K S E Y A P S E K
Chimpanzee Pan troglodytes XP_507662 338 38544 S109 R D V T I S K S E Y A P S E K
Rhesus Macaque Macaca mulatta XP_001085862 338 38670 S109 R D V T I S K S E Y T P S E K
Dog Lupus familis XP_535184 540 60291 S311 R D V S I A K S E Y I P S E R
Cat Felis silvestris
Mouse Mus musculus O35386 338 38589 Q109 R D V A L A K Q D Y M P S D R
Rat Rattus norvegicus P57093 338 38570 Q109 K D V A I A K Q G Y A P S E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424238 289 33402 R73 D N G Y L L I R K L V S D E D
Frog Xenopus laevis NP_001086497 334 38166 S106 R D I A I S K S E Y V P D Q K
Zebra Danio Brachydanio rerio NP_001017823 335 38486 S106 K D V S I A K S E F V E G E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62515 312 35701 K76 S I A K S E F K D G E K A I T
Sea Urchin Strong. purpuratus XP_784265 255 28831 D40 R A I N K L Q D F Q D N E V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.2 50 N.A. 78.1 78.1 N.A. N.A. 54.4 69.8 68.3 N.A. N.A. N.A. 55 49.4
Protein Similarity: 100 99.4 97.3 55.5 N.A. 87.8 89 N.A. N.A. 67.7 80.4 81.3 N.A. N.A. N.A. 71.3 61.5
P-Site Identity: 100 100 93.3 73.3 N.A. 46.6 60 N.A. N.A. 6.6 66.6 53.3 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 80 N.A. N.A. 26.6 80 80 N.A. N.A. N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 28 0 37 0 0 0 0 28 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 73 0 0 0 0 0 10 19 0 10 0 19 10 10 % D
% Glu: 0 0 0 0 0 10 0 0 55 0 10 10 10 64 0 % E
% Phe: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 10 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 19 0 64 0 10 0 0 0 10 0 0 10 0 % I
% Lys: 19 0 0 10 10 0 73 10 10 0 0 10 0 0 46 % K
% Leu: 0 0 0 0 19 19 0 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 19 0 10 0 0 0 10 0 % Q
% Arg: 64 0 0 0 0 0 0 10 0 0 0 0 0 0 28 % R
% Ser: 10 0 0 19 10 37 0 55 0 0 0 10 55 0 0 % S
% Thr: 0 0 0 28 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 0 0 64 0 0 0 0 0 0 0 28 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 64 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _