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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYH All Species: 34.55
Human Site: S266 Identified Species: 76
UniProt: O14832 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14832 NP_006205.1 338 38538 S266 H P L L I H G S G Q N K T Q G
Chimpanzee Pan troglodytes XP_507662 338 38544 S266 H P L L I H G S G Q N K T Q G
Rhesus Macaque Macaca mulatta XP_001085862 338 38670 S266 H P L L I H G S G Q N K T Q G
Dog Lupus familis XP_535184 540 60291 S468 H P L L I H G S G W N R T Q G
Cat Felis silvestris
Mouse Mus musculus O35386 338 38589 S266 H P L L I H G S G R N K T Q G
Rat Rattus norvegicus P57093 338 38570 S266 H P L L I H G S G R N R T Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424238 289 33402 W227 K P H G Y P E W E G K T N K L
Frog Xenopus laevis NP_001086497 334 38166 S263 H P L L I H G S G M N K T A G
Zebra Danio Brachydanio rerio NP_001017823 335 38486 S263 H P L L I H G S G M N Q T N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O62515 312 35701 S233 H P I L I H G S G A N R T E G
Sea Urchin Strong. purpuratus XP_784265 255 28831 A194 K T S G F R K A I S C H Y A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 95.2 50 N.A. 78.1 78.1 N.A. N.A. 54.4 69.8 68.3 N.A. N.A. N.A. 55 49.4
Protein Similarity: 100 99.4 97.3 55.5 N.A. 87.8 89 N.A. N.A. 67.7 80.4 81.3 N.A. N.A. N.A. 71.3 61.5
P-Site Identity: 100 100 100 86.6 N.A. 93.3 86.6 N.A. N.A. 6.6 86.6 80 N.A. N.A. N.A. 73.3 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 13.3 86.6 86.6 N.A. N.A. N.A. 93.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 10 0 0 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 10 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 19 0 0 82 0 82 10 0 0 0 0 82 % G
% His: 82 0 10 0 0 82 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 82 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 19 0 0 0 0 0 10 0 0 0 10 46 0 10 0 % K
% Leu: 0 0 73 82 0 0 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 82 0 10 10 0 % N
% Pro: 0 91 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 28 0 10 0 55 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 19 0 28 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 82 0 10 0 0 0 0 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 10 82 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _